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Reliability of the 2- and 6-minute walk tests in neuromuscular diseases

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OBJECTIVE: The 2- and 6-minute walk tests are used to evaluate walking capacity, but reliability has been sparsely investigated in patients with neuromuscular diseases. The aim of this study was to investigate the relative and absolute reliability of the 2- and 6-minute walk tests in patients with neuromuscular diseases.

DESIGN: Each patient performed a 2- and a 6-minute walk test on 2 test days separated by 1-2 weeks.

SUBJECTS: A total of 93 adult patients (mean age 53 years, age range 22-83 years) with 12 different neuromuscular diseases were included.

RESULTS: The mean walking distance increased by 4.3 and 11.2 m (p < 0.001) in repeated 2- and 6-minute walk tests, respectively. Intraclass correlation coefficient in the 2- and 6-minute walk tests was 0.99 (p < 0.001). Standard error of measurement was 4.9 m in the 2-minute walk test and 14.0 m in the 6-minute walk test. Minimal detectable difference was 13.7 m in the 2-minute walk test and 38.8 m in the 6-minute walk test.

CONCLUSION: These findings show good relative reliability of the 2- and 6-minute walk tests in patients with neuromuscular diseases. However, absolute reliability demonstrated variability in neuromuscular diseases. This should be considered when interpreting a change in walking distance.

Original languageEnglish
JournalJournal of Rehabilitation Medicine
Volume49
Issue number4
Pages (from-to)362-366
Number of pages5
ISSN1650-1977
DOIs
Publication statusPublished - 6 Apr 2017

    Research areas

  • Adult, Aged, Aged, 80 and over, Exercise Test, Female, Humans, Male, Middle Aged, Neuromuscular Diseases, Reproducibility of Results, Walk Test, Young Adult, Journal Article

ID: 52120179