Relative atrial natriuretic peptide deficiency and inadequate renin and angiotensin II suppression in obese hypertensive men

Camilla L Asferg; Søren J Nielsen; Ulrik B Andersen; Allan Linneberg; Daniel V Møller; Paula L Hedley; Michael Christiansen; Jens P Goetze; Murray Esler; Jørgen L Jeppesen

doi:10.1161/HYPERTENSIONAHA.111.00791

Relative atrial natriuretic peptide deficiency and inadequate renin and angiotensin II suppression in obese hypertensive men

Camilla L Asferg, Søren J Nielsen, Ulrik B Andersen, Allan Linneberg, Daniel V Møller, Paula L Hedley, Michael Christiansen, Jens P Goetze, Murray Esler, Jørgen L Jeppesen

56 Citations (Scopus)

Abstract

Obesity is a strong risk factor for hypertension, but the mechanisms by which obesity leads to hypertension are incompletely understood. On this background, we assessed dietary sodium intake, serum levels of natriuretic peptides (NPs), and the activity of the renin-angiotensin system in 63 obese hypertensive men (obeseHT: body mass index, ≥30.0 kg/m(2); 24-hour ambulatory blood pressure, ≥130/80 mm Hg), in 40 obese normotensive men (obeseNT: body mass index, ≥30.0 kg/m(2); 24-hour ambulatory blood pressure,

Original language	English
Journal	Hypertension
Volume	62
Issue number	1
Pages (from-to)	147-53
Number of pages	7
ISSN	0194-911X
DOIs	https://doi.org/10.1161/HYPERTENSIONAHA.111.00791
Publication status	Published - Jul 2013

Keywords

Adult
Aged
Angiotensin II
Atrial Natriuretic Factor
Blood Pressure
Blood Pressure Monitoring, Ambulatory
Body Composition
Follow-Up Studies
Humans
Hypertension
Male
Middle Aged
Obesity
Prognosis
Renin
Renin-Angiotensin System

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10.1161/HYPERTENSIONAHA.111.00791

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title = "Relative atrial natriuretic peptide deficiency and inadequate renin and angiotensin II suppression in obese hypertensive men",

abstract = "Obesity is a strong risk factor for hypertension, but the mechanisms by which obesity leads to hypertension are incompletely understood. On this background, we assessed dietary sodium intake, serum levels of natriuretic peptides (NPs), and the activity of the renin-angiotensin system in 63 obese hypertensive men (obeseHT: body mass index, ≥30.0 kg/m(2); 24-hour ambulatory blood pressure, ≥130/80 mm Hg), in 40 obese normotensive men (obeseNT: body mass index, ≥30.0 kg/m(2); 24-hour ambulatory blood pressure, ",

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author = "Asferg, {Camilla L} and Nielsen, {S{\o}ren J} and Andersen, {Ulrik B} and Allan Linneberg and M{\o}ller, {Daniel V} and Hedley, {Paula L} and Michael Christiansen and Goetze, {Jens P} and Murray Esler and Jeppesen, {J{\o}rgen L}",

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AU - Asferg, Camilla L

AU - Nielsen, Søren J

AU - Andersen, Ulrik B

AU - Linneberg, Allan

AU - Møller, Daniel V

AU - Hedley, Paula L

AU - Christiansen, Michael

AU - Goetze, Jens P

AU - Esler, Murray

AU - Jeppesen, Jørgen L

PY - 2013/7

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KW - Aged

KW - Angiotensin II

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KW - Blood Pressure

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KW - Body Composition

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KW - Humans

KW - Hypertension

KW - Male

KW - Middle Aged

KW - Obesity

KW - Prognosis

KW - Renin

KW - Renin-Angiotensin System

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DO - 10.1161/HYPERTENSIONAHA.111.00791

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SP - 147

EP - 153

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IS - 1

ER -

Relative atrial natriuretic peptide deficiency and inadequate renin and angiotensin II suppression in obese hypertensive men

Abstract

Keywords

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