Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Regional cerebral blood flow before and after vascular surgery in patients with transient ischemic attacks with 133-xenon inhalation tomography

Research output: Contribution to journalJournal articleResearchpeer-review

  1. A totally new system is needed for drug research and development

    Research output: Contribution to journalLetterResearchpeer-review

  2. Patients not patents: Drug research and development as a public enterprise

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Prediction of coronary heart disease or heart failure using high-sensitivity cardiac troponin T: a pilot study

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Anti-inflammatory effects of exercise: role in diabetes and cardiovascular disease

    Research output: Contribution to journalReviewResearchpeer-review

  5. Familial hypercholesterolaemia: cholesterol efflux and coronary disease

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Mishandling af psykiatri

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Faelles vaerdigrundlag for alle voksne med psykisk sygdom er en utopi

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Dopamine D(2) receptor quantification in extrastriatal brain regions using [(123)I]epidepride with bolus/infusion

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Vestibularis-schwannomers diagnostik og vaekst bedømt ved SPECT kombineret med TL-201 Thallium

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Activation-induced resetting of cerebral oxygen and glucose uptake in the rat

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations
Cerebral blood flow CBF was studied in 14 patients with transient ischemic attacks TIA and arteriosclerotic neck vessel disease. CBF was measured by a rapidly rotating single photon emission computerized tomograph using Xenon-133 inhalation. This method yields images of 3 brain slices depicting CBF with a spatial resolution of 1.7 cm. Based primarily on the clinical evidence and on the angiographical findings embolism was considered the pathogenetic factor in 10 cases, whereas chronic hemodynamic insufficiency rendered symptomatic by postural factors probably accounted for the symptoms in 4 patients. Of the 14 patients, all studied days to weeks after the most recent TIA, four showed hypoperfused areas on the CBF-tomograms and with roughly the same location hypodense areas on CT-scanning, i.e. areas of complete infarction. However, an additional five patients showed reduction of CBF in areas with no abnormality on the CT-scan. The abnormal blood flow pattern was found to be unchanged after clinically successful reconstructive vascular surgery. This suggests the presence of irreversible ischemic tissue damage without gross emollition (incomplete infarction). It is concluded, that TIAs are often harmful events, as no less than 9 of the 14 patients studied had evidence of complete and/or incomplete infarction. Thorough examination and rational therapy should be instituted as soon as possible to prevent further ischemic lesions.

Original languageEnglish
JournalEuropean Journal of Clinical Investigation
Issue number12
ISSN0014-2972
Publication statusPublished - 1982

ID: 44344898