Abstract
A survey of the Xenon-133 techniques for measurement of regional cerebral blood flow, rCBF, in man is presented. The intra-arterial Xe-133 injection method is very sensitive for detecting even small hyperemic areas, but cannot "see" smaller ischemic areas. The Xe-133 inhalation (or i.v. inj.) technique is insensitive both to hyperemia and ischemia yielding essentially only a mean flow value. A new rapidly moving single photon tomograph following D. Kuhl's principle is presented applicable to Xe-133. Preliminary clinical data show that this technique is able to detect ischemic areas both with Xe-133 intra-arterial injection and with Xe-133 inhalation. The practical and economic advantages of Xe-133 or Xe-127 tomography over positron tomography for rCBF are discussed.
Original language | English |
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Journal | Bulletin der Schweizerischen Akademie der Medizinischen Wissenschaften |
Volume | 36 |
Issue number | 1-3 |
Pages (from-to) | 93-100 |
Number of pages | 8 |
ISSN | 0036-7494 |
Publication status | Published - Apr 1980 |
Keywords
- Administration, Intranasal
- Brain Ischemia
- Cerebral Arteries
- Cerebrovascular Circulation
- Humans
- Hyperemia
- Injections, Intra-Arterial
- Tomography, Emission-Computed
- Xenon Radioisotopes