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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Recommendations for Implementing Lung Cancer Screening with Low-Dose Computed Tomography in Europe

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  • Giulia Veronesi
  • David R Baldwin
  • Claudia I Henschke
  • Simone Ghislandi
  • Sergio Iavicoli
  • Matthijs Oudkerk
  • Harry J De Koning
  • Joseph Shemesh
  • John K Field
  • Javier J Zulueta
  • Denis Horgan
  • Lucia Fiestas Navarrete
  • Maurizio Valentino Infante
  • Pierluigi Novellis
  • Rachael L Murray
  • Nir Peled
  • Cristiano Rampinelli
  • Gaetano Rocco
  • Witold Rzyman
  • Giorgio Vittorio Scagliotti
  • Martin C Tammemagi
  • Luca Bertolaccini
  • Natthaya Triphuridet
  • Rowena Yip
  • Alexia Rossi
  • Suresh Senan
  • Giuseppe Ferrante
  • Kate Brain
  • Carlijn van der Aalst
  • Lorenzo Bonomo
  • Dario Consonni
  • Jan P Van Meerbeeck
  • Patrick Maisonneuve
  • Silvia Novello
  • Anand Devaraj
  • Zaigham Saghir
  • Giuseppe Pelosi
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Lung cancer screening (LCS) with low-dose computed tomography (LDCT) was demonstrated in the National Lung Screening Trial (NLST) to reduce mortality from the disease. European mortality data has recently become available from the Nelson randomised controlled trial, which confirmed lung cancer mortality reductions by 26% in men and 39-61% in women. Recent studies in Europe and the USA also showed positive results in screening workers exposed to asbestos. All European experts attending the "Initiative for European Lung Screening (IELS)"-a large international group of physicians and other experts concerned with lung cancer-agreed that LDCT-LCS should be implemented in Europe. However, the economic impact of LDCT-LCS and guidelines for its effective and safe implementation still need to be formulated. To this purpose, the IELS was asked to prepare recommendations to implement LCS and examine outstanding issues. A subgroup carried out a comprehensive literature review on LDCT-LCS and presented findings at a meeting held in Milan in November 2018. The present recommendations reflect that consensus was reached.

Original languageEnglish
JournalCancers
Volume12
Issue number6
ISSN2072-6694
DOIs
Publication statusPublished - 24 Jun 2020

ID: 62376293