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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Real-world evidence to guide healthcare policies in oncology

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Correction: Calcium electroporation for treatment of sarcoma in preclinical studies

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  2. Expression and function of Kv1.3 channel in malignant T cells in Sézary syndrome

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  3. Cell-free DNA in newly diagnosed patients with glioblastoma - a clinical prospective feasibility study

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  1. Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Tertiary lymphoid structures improve immunotherapy and survival in melanoma

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. The real-world outcome of metastatic melanoma: Unknown primary vs. known cutaneous

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Long-Term Exposure to Inflammation Induces Differential Cytokine Patterns and Apoptosis in Dendritic Cells

    Research output: Contribution to journalJournal articleResearchpeer-review

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Randomized controlled clinical trials (RCTs) in oncology enroll patients who meet strict protocol-specified criteria. Many of these criteria overlap across multiple RCTs. A vast proportion of patients with metastatic cancer do not meet such criteria. Hence, patient populations encountered in clinical practice are essentially different from RCT-populations, questioning the representativeness of these trials. A real-world evidence approach, using data from clinical practice, is increasingly employed to complement the information on drug safety and efficacy obtained from traditional clinical trials.

Original languageEnglish
JournalOncotarget
Volume10
Issue number44
Pages (from-to)4513-4515
Number of pages3
ISSN1949-2553
DOIs
Publication statusPublished - 16 Jul 2019

ID: 57727604