Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Real-world effectiveness and safety of pharmacological thromboprophylaxis in patients undergoing primary total hip and knee arthroplasty: A narrative review

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Secondary stroke prophylaxis in atrial fibrillation patients with chronic kidney disease: a nationwide cohort study

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Pharmacogenetics of antiemetics for chemotherapy-induced nausea and vomiting: A systematic review and meta-analysis

    Research output: Contribution to journalReviewResearchpeer-review

  3. Rivaroxaban Versus Apixaban for Stroke Prevention in Atrial Fibrillation: An Instrumental Variable Analysis of a Nationwide Cohort

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. One-year outcomes in atrial fibrillation presenting during infections: a nationwide registry-based study

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Glycemic control and use of glucose-lowering medications in hospital-admitted type 2 diabetes patients over 80 years

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations
In this narrative review of the real-world effectiveness and safety of pharmacological thromboprophylaxis following primary total hip and knee arthroplasty, a total of 12 non-interventional observational studies were included. Pharmacological thromboprophylaxis included warfarin, heparins, dabigatran, rivaroxaban, apixaban, acetylsalicylic acid, and fondaparinux. The absolute risks varied across the included studies. These variations can be explained by differences in patient populations, drug exposure, follow-up time, and definition of outcomes, which makes it a challenge to compare the risk estimates. These findings emphasize the need for a large population-based real-world study to provide comparable risk estimates associated with different pharmacological thromboprophylaxis.
Original languageEnglish
Article numberhttps://doi.org/10.1016/j.jor.2019.11.012
JournalJournal of Orthopaedics
ISSN0972-978X
Publication statusPublished - 12 Nov 2019

ID: 58644597