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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Rationel behandling af ukontrollable, livstruende blødninger med anvendelse af rekombinant faktor VIIa

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We present a standardised treatment algorithm used to treat life-threatening haemorrhage (LTH) due to trauma, surgery, or delivery at Rigshospitalet, Copenhagen University Hospital, Balanced transfusion therapy and infusion of fibrinogen must precede recombinant factor Vila (rFVIIa) treatment. rFVIIa is indicated in patients with uncontrollable LTH (> 1 blood component per 10 kg of whole body weight per hour) despite surgical treatment and adequately balanced transfusion. We recommend rFVIIa at a dose of 100 μ g/kg. The dosage recommendation is not evidence-based. A thorough, prospective surveillance program to monitor the treatment's efficacy and safety is therefore mandatory. The Blood Bank services, guides and coordinates the treatment.

Translated title of the contributionRecombinant factor VIIa treatment in patients with uncontrollable, life-threating haemorrhage, an algorithm-based approach
Original languageDanish
JournalUgeskrift for Laeger
Volume167
Issue number25-31
Pages (from-to)2756-2759
Number of pages4
ISSN0041-5782
Publication statusPublished - 20 Jun 2005

ID: 58272876