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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Rates of Very Preterm Birth in Europe and Neonatal Mortality Rates

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  1. EPICE cohort: two-year neurodevelopmental outcomes after very preterm birth

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Milk feed osmolality and adverse events in newborn infants and animals: a systematic review

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  3. Breastfeeding outcomes in European NICUs: impact of parental visiting policies

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  4. Cerebral oxygenation and blood flow in term infants during postnatal transition: BabyLux project

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  1. Akutte alvorlige sygdomme hos gravide og fødende

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  2. Characteristics, management and outcomes of very preterm triplets in 19 European regions

    Research output: Contribution to journalJournal articleResearchpeer-review

  • David John Field
  • Elizabeth S Draper
  • Alan Fenton
  • Emile Papiernik
  • J Zeitlin
  • Beatrice Blondel
  • Marina Cuttini
  • Rolf Maier
  • Tom Weber
  • Manuel Carrapato
  • Louis A Kollee
  • Janusz Gadzinowski
  • Patrick Van Reempts
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OBJECTIVE: To estimate the influence of variation in the rate of very preterm delivery on the reported rate of neonatal death in ten European regions. DESIGN: Comparison of 10 separate geographically defined European populations, from nine European countries, over a one year period (seven months in one region). PARTICIPANTS: All births that occurred between 22+0 and 31+6 weeks of gestation in 2003. MAIN OUTCOME MEASURE: Neonatal death rate adjusted for rate of delivery at this gestation. RESULTS: Rate of delivery of all births at 22+0-31+6 weeks of gestation and live births only were calculated for each region. Two regions had significantly higher rates of very preterm delivery per 1000 births (Trent UK (16.8, 95% CI 15.7-17.9) and the Northern UK (17.1, 95% CI 15.6-18.6); group mean 13.2, 95% CI 12.9 to 13.5). Four regions had rates significantly below the group average: Portugal North (10.7, 95% CI 9.6 to 11.8), Eastern and Central Netherlands (10.6, 95% CI 9.7 to 11.6), Eastern Denmark (11.2, 95% CI 10.1 to 12.4) and Lazio in Italy (11.0, 95% CI 10.1 to 11.9). Similar trends were seen in live birth data. Published rates of neonatal death for each region were then adjusted by applying: a) a standardised rate of very preterm delivery and b) the existing death rate for babies born at this gestation in the individual region. This produced much greater homogeneity in terms of neonatal mortality. CONCLUSIONS: Variation in the rate of very preterm delivery has a major influence on reported neonatal death rates.
Original languageEnglish
JournalArchives of Disease in Childhood. Fetal and Neonatal Edition
Volume94
Pages (from-to)F253-56
ISSN1359-2998
DOIs
Publication statusPublished - 2008

ID: 32525541