Rapid morphological changes and loss of collagen following experimental acute colonic obstruction

Peter-Martin Krarup; Martin Rehn; Janna Sand-Dejmek; Roy Ehrnström; Sven Per Magnus Ågren; Ingvar Syk

doi:10.1007/s00384-012-1548-x

Rapid morphological changes and loss of collagen following experimental acute colonic obstruction

Peter-Martin Krarup, Martin Rehn, Janna Sand-Dejmek, Roy Ehrnström, Sven Per Magnus Ågren, Ingvar Syk

4 Citations (Scopus)

Abstract

Anastomosis of an acutely obstructed colon is associated with an increased risk of dehiscence. In experimental models, acute obstruction decreases collagen in the colonic wall, but the time course and propagation along the colon of the biochemical changes are unknown. Furthermore, there is a paucity of information on the correlation between these biochemical changes and histological features.

Original language	English
Journal	International Journal of Colorectal Disease
Volume	28
Issue number	3
Pages (from-to)	341-7
Number of pages	7
ISSN	0179-1958
DOIs	https://doi.org/10.1007/s00384-012-1548-x
Publication status	Published - 2013

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title = "Rapid morphological changes and loss of collagen following experimental acute colonic obstruction",

abstract = "Anastomosis of an acutely obstructed colon is associated with an increased risk of dehiscence. In experimental models, acute obstruction decreases collagen in the colonic wall, but the time course and propagation along the colon of the biochemical changes are unknown. Furthermore, there is a paucity of information on the correlation between these biochemical changes and histological features.",

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T1 - Rapid morphological changes and loss of collagen following experimental acute colonic obstruction

AU - Krarup, Peter-Martin

AU - Rehn, Martin

AU - Sand-Dejmek, Janna

AU - Ehrnström, Roy

AU - Ågren, Sven Per Magnus

AU - Syk, Ingvar

PY - 2013

Y1 - 2013

N2 - Anastomosis of an acutely obstructed colon is associated with an increased risk of dehiscence. In experimental models, acute obstruction decreases collagen in the colonic wall, but the time course and propagation along the colon of the biochemical changes are unknown. Furthermore, there is a paucity of information on the correlation between these biochemical changes and histological features.

AB - Anastomosis of an acutely obstructed colon is associated with an increased risk of dehiscence. In experimental models, acute obstruction decreases collagen in the colonic wall, but the time course and propagation along the colon of the biochemical changes are unknown. Furthermore, there is a paucity of information on the correlation between these biochemical changes and histological features.

UR - https://www.scopus.com/pages/publications/84879460266

U2 - 10.1007/s00384-012-1548-x

DO - 10.1007/s00384-012-1548-x

M3 - Journal article

C2 - 22903297

SN - 0179-1958

VL - 28

SP - 341

EP - 347

JO - International Journal of Colorectal Disease

JF - International Journal of Colorectal Disease

IS - 3

ER -

Rapid morphological changes and loss of collagen following experimental acute colonic obstruction

Abstract

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