Randomized trial of oral teriflunomide for relapsing multiple sclerosis

Paul O'Connor; Jerry S Wolinsky; Christian Confavreux; Giancarlo Comi; Ludwig Kappos; Tomas P Olsson; Hadj Benzerdjeb; Philippe Truffinet; Lin Wang; Aaron Miller; Mark S Freedman; TEMSO Trial Group; Jette Lautrup Battistini Frederiksen

doi:10.1056/NEJMoa1014656

Randomized trial of oral teriflunomide for relapsing multiple sclerosis

Paul O'Connor, Jerry S Wolinsky, Christian Confavreux, Giancarlo Comi, Ludwig Kappos, Tomas P Olsson, Hadj Benzerdjeb, Philippe Truffinet, Lin Wang, Aaron Miller, Mark S Freedman, TEMSO Trial Group, Jette Lautrup Battistini Frederiksen

Department of Neurology

847 Citations (Scopus)

Abstract

Teriflunomide is a new oral disease-modifying therapy for relapsing forms of multiple sclerosis.

Original language	English
Journal	New England Journal of Medicine
Volume	365
Issue number	14
Pages (from-to)	1293-303
Number of pages	11
ISSN	0028-4793
DOIs	https://doi.org/10.1056/NEJMoa1014656
Publication status	Published - 2011

Keywords

Administration, Oral
Adult
Alanine Transaminase
Brain
Crotonic Acids
Disability Evaluation
Disease Progression
Enzyme Inhibitors
Fatigue
Female
Humans
Male
Middle Aged
Multiple Sclerosis, Relapsing-Remitting
Oxidoreductases Acting on CH-CH Group Donors
Recurrence
Toluidines
Young Adult

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10.1056/NEJMoa1014656

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@article{ce40ca603c6745b38c05e1655332740d,

title = "Randomized trial of oral teriflunomide for relapsing multiple sclerosis",

abstract = "Teriflunomide is a new oral disease-modifying therapy for relapsing forms of multiple sclerosis.",

keywords = "Administration, Oral, Adult, Alanine Transaminase, Brain, Crotonic Acids, Disability Evaluation, Disease Progression, Enzyme Inhibitors, Fatigue, Female, Humans, Male, Middle Aged, Multiple Sclerosis, Relapsing-Remitting, Oxidoreductases Acting on CH-CH Group Donors, Recurrence, Toluidines, Young Adult",

author = "Paul O'Connor and Wolinsky, {Jerry S} and Christian Confavreux and Giancarlo Comi and Ludwig Kappos and Olsson, {Tomas P} and Hadj Benzerdjeb and Philippe Truffinet and Lin Wang and Aaron Miller and Freedman, {Mark S} and {TEMSO Trial Group} and Frederiksen, {Jette Lautrup Battistini}",

year = "2011",

doi = "10.1056/NEJMoa1014656",

language = "English",

volume = "365",

pages = "1293--303",

journal = "New England Journal of Medicine",

issn = "0028-4793",

publisher = "Massachusetts Medical Society",

number = "14",

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TY - JOUR

T1 - Randomized trial of oral teriflunomide for relapsing multiple sclerosis

AU - O'Connor, Paul

AU - Wolinsky, Jerry S

AU - Confavreux, Christian

AU - Comi, Giancarlo

AU - Kappos, Ludwig

AU - Olsson, Tomas P

AU - Benzerdjeb, Hadj

AU - Truffinet, Philippe

AU - Wang, Lin

AU - Miller, Aaron

AU - Freedman, Mark S

AU - TEMSO Trial Group

AU - Frederiksen, Jette Lautrup Battistini

PY - 2011

Y1 - 2011

N2 - Teriflunomide is a new oral disease-modifying therapy for relapsing forms of multiple sclerosis.

AB - Teriflunomide is a new oral disease-modifying therapy for relapsing forms of multiple sclerosis.

KW - Administration, Oral

KW - Adult

KW - Alanine Transaminase

KW - Brain

KW - Crotonic Acids

KW - Disability Evaluation

KW - Disease Progression

KW - Enzyme Inhibitors

KW - Fatigue

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Multiple Sclerosis, Relapsing-Remitting

KW - Oxidoreductases Acting on CH-CH Group Donors

KW - Recurrence

KW - Toluidines

KW - Young Adult

U2 - 10.1056/NEJMoa1014656

DO - 10.1056/NEJMoa1014656

M3 - Journal article

C2 - 21991951

SN - 0028-4793

VL - 365

SP - 1293

EP - 1303

JO - New England Journal of Medicine

JF - New England Journal of Medicine

IS - 14

ER -

Randomized trial of oral teriflunomide for relapsing multiple sclerosis

Abstract

Keywords

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