Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Quantification of visceral adipose tissue in polycystic ovary syndrome: dual-energy X-ray absorptiometry versus magnetic resonance imaging

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. Grading lumbar disc degeneration: a comparison between low- and high-field MRI

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. The effects of rotation on radiological parameters in the spine

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. The efficacy of using computer-aided detection (CAD) for detection of breast cancer in mammography screening: a systematic review

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. New section editor: Cardiac Imaging

    Research output: Contribution to journalJournal articleCommunication

  1. Empagliflozin in heart failure patients with reduced ejection fraction: a randomized clinical trial (Empire HF)

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Effects of Dapagliflozin on Volume Status When Added to Renin-Angiotensin System Inhibitors

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Prevalence of heart failure and the diagnostic value of MR-proANP in outpatients with type 2 diabetes

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

Background Polycystic ovary syndrome (PCOS) is associated with frequent overweight and abdominal obesity. Quantifying visceral adipose tissue (VAT) in PCOS patients can be a tool to assess metabolic risk and monitor effects of treatment. The latest dual-energy X-ray absorptiometry (DXA) technology can measure VAT and subcutaneous adipose tissue (SAT) in a clinical setting. Purpose To compare DXA-measurements of VAT and SAT with the gold standard MRI in women with PCOS. Material and Methods A cross-sectional study of 67 overweight women with PCOS was performed. Measurements of VAT and SAT were performed by DXA in a 5-cm thick transverse slice at the L4/L5 level and by MRI in a 1-cm thick transverse slice at the L3 level. Results Mean (SD) DXA-VAT was 81 (34) cm3, DXA-SAT was 498 (118) cm3, MRI-VAT was 117 (48) cm3, and MRI-SAT was 408 (122) cm3. MRI and DXA measures of VAT (r = 0.82, P < 0.001) and SAT (r = 0.92, P < 0.001) correlated closely, and DXA-VAT was stronger correlated with MRI-VAT than BMI (r = 0.62, P < 0.001) and waist circumference (r = 0.60, P < 0.001). DXA-VAT coefficient of variance was 6.7% and inter correlation coefficient was 0.98. Bland-Altman analyses showed DXA to slightly underestimate VAT and SAT measurements compared with MRI. Conclusion DXA and MRI measurements of VAT and SAT correlated closely despite different size of region of interest, and DXA-VAT was superior to waist circumference and BMI in estimating MRI-VAT. DXA showed high reproducibility making it is suitable for repeated measurements in the same individual over time.

Original languageEnglish
JournalActa Radiologica
Volume59
Issue number1
Pages (from-to)13-17
Number of pages5
ISSN0284-1851
DOIs
Publication statusPublished - Jan 2018

    Research areas

  • Abdomen, Absorptiometry, Photon, Adult, Cross-Sectional Studies, Female, Humans, Intra-Abdominal Fat, Magnetic Resonance Imaging, Polycystic Ovary Syndrome, Reproducibility of Results, Comparative Study, Journal Article

ID: 52541578