Abstract
In-vivo Manganese-Enhanced MRI (MEMRI) studies have shown important potential in rodents for the delineation of cytoarchitectural brain features and of functional details. Ex-vivo MEMRI on the other hand offers the possibility to investigate brain microstructure and function with improved spatial resolution and no motion artefacts. Here, ex-vivo lamb brains were immersed in a highly concentrated MnCl2 solution for a month and revealed interesting cytoarchitectural features already 24 hours after immersion and up to 3 months after the end of immersion on MPRAGE images at 3T. A novel ex-vivo MEMRI approach is proposed, which could benefit MEMRI translation to human studies.
| Original language | English |
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| Publication date | 11 May 2022 |
| Publication status | Published - 11 May 2022 |
| Event | Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting - London, Englnd, UK Duration: 7 May 2022 → 12 May 2022 https://www.ismrm.org/22m/ |
Conference
| Conference | Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting |
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| Location | London, Englnd, UK |
| Period | 07/05/2022 → 12/05/2022 |
| Internet address |