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Putting the spotlight on donation-related risks and donor safety - are we succeeding in protecting donors?

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. Determinants of intention to return to donate blood among first-time blood donors in Ghana

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. How donor selection criteria can be evaluated with limited scientific evidence: lessons learned from the TRANSPOSE project

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Impact of long-term storage of plasma and cell-free DNA on measured DNA quantity and fetal fraction

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. External quality assessment of noninvasive fetal RHD genotyping

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Freeze-dried plasma in major haemorrhage: a systematic review

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Comparison of 16 Serological SARS-CoV-2 Immunoassays in 16 Clinical Laboratories

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Determinants of intention to return to donate blood among first-time blood donors in Ghana

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. How donor selection criteria can be evaluated with limited scientific evidence: lessons learned from the TRANSPOSE project

    Research output: Contribution to journalJournal articleResearchpeer-review

  • Christina Mikkelsen
  • Gaia Mori
  • Suzanna M van Walraven
  • Johanna Castrén
  • Sharon Zahra
  • Sheila MacLennan
  • Kirsten Seidel
  • Stefano Fontana
  • Eva Veropalumbo
  • Livia Cannata
  • Simonetta Pupella
  • Maria Kvist
  • Marjan Happel
  • Piia Korkalainen
  • Birgit Wulff
  • Jesus Fernandez-Sojo
  • Cristina Eguizabal
  • Fernando Urbano
  • Miguel Angel Vesga
  • Primoz Pozenel
  • Marian van Kraaij
  • Morten Bagge Hansen
  • Ed Slot
  • Henrik Ullum
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BACKGROUND AND OBJECTIVE: The European consortium project TRANSPOSE (TRANSfusion and transplantation: PrOtection and SElection of donors) aimed to assess and evaluate the risks to donors of Substances of Human Origin (SoHO), and to identify gaps between current donor vigilance systems and perceived risks.

MATERIALS AND METHODS: National and local data from participating organizations on serious and non-serious adverse reactions in donors were collected from 2014 to 2017. Following this, a survey was performed among participants to identify risks not included in the data sets. Finally, participants rated the risks according to severity, level of evidence and prevalence.

RESULTS: Significant discrepancies between anticipated donor risks and the collected data were found. Furthermore, many participants reported that national data on adverse reactions in donors of stem cells, gametes, embryos and tissues were not routinely collected and/or available.

CONCLUSIONS: These findings indicate that there is a need to further develop and standardize donor vigilance in Europe and to include long-term risks to donors, which are currently underreported, ensuring donor health and securing the future supply of SoHO.

Original languageEnglish
JournalVox Sanguinis
Volume116
Issue number3
Pages (from-to)313-323
Number of pages11
ISSN0042-9007
DOIs
Publication statusPublished - Mar 2021

    Research areas

  • blood safety, donors, donor health, hemovigilance

ID: 61696460