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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Pulmonary arterial lesions in explanted lungs after transplantation correlate with severity of pulmonary hypertension in chronic obstructive pulmonary disease

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  4. An ISHLT consensus document for prevention and management strategies for mechanical circulatory support infection

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  1. Lung Ultrasound in the Assessment of Pulmonary Complications After Lung Transplantation

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  2. Uafklaret dyspnø.

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  3. Relationship Between Invasive Hemodynamics and Liver Function in Advanced Heart Failure

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BACKGROUND: Pulmonary vascular findings are largely unreported in end-stage chronic obstructive pulmonary disease (COPD). METHODS: Pulmonary vascular lesions in explanted lungs from 70 patients with COPD/emphysema or α-1-antitrypsin deficiency were analyzed retrospectively. Patients were stratified by the presence and severity of pulmonary hypertension (PH) assessed by right-heart catheterization in 3 hemodynamically distinct groups: (1) non-PH (mean pulmonary arterial pressure [mPAP]50 mm Hg; median HE Grade 4 (range 3-6), with generalized arterial dilatation and plexiform lesions. CONCLUSIONS: The extent of pulmonary vascular lesions in COPD correlate with the severity of PH. Morphologic lesions similar to those characteristic of IPAH can be observed as PH in COPD progresses to levels characteristic of IPAH.
Original languageEnglish
JournalJournal of Heart and Lung Transplantation
Volume32
Issue number3
Pages (from-to)347-354
ISSN1053-2498
DOIs
Publication statusPublished - 2013

ID: 36590578