TY - JOUR
T1 - Proposal for the standardisation of multi-centre trials in nuclear medicine imaging
T2 - prerequisites for a European 123I-FP-CIT SPECT database
AU - Dickson, John Caddell
AU - Tossici-Bolt, Livia
AU - Sera, Terez
AU - de Nijs, Robin
AU - Booij, Jan
AU - Bagnara, Maria Claudia
AU - Seese, Anita
AU - Koulibaly, Pierre Malick
AU - Akdemir, Umit Ozgur
AU - Jonsson, Cathrine
AU - Koole, Michel
AU - Raith, Maria
AU - Lonsdale, Markus Nowak
AU - George, Jean
AU - Zito, Felicia
AU - Tatsch, Klaus
PY - 2012
Y1 - 2012
N2 - Multi-centre trials are an important part of proving the efficacy of procedures, drugs and interventions. Imaging components in such trials are becoming increasingly common; however, without sufficient control measures the usefulness of these data can be compromised. This paper describes a framework for performing high-quality multi-centre trials with single photon emission computed tomography (SPECT), using a pan-European initiative to acquire a normal control dopamine transporter brain scan database as an example.
AB - Multi-centre trials are an important part of proving the efficacy of procedures, drugs and interventions. Imaging components in such trials are becoming increasingly common; however, without sufficient control measures the usefulness of these data can be compromised. This paper describes a framework for performing high-quality multi-centre trials with single photon emission computed tomography (SPECT), using a pan-European initiative to acquire a normal control dopamine transporter brain scan database as an example.
KW - Clinical Trials as Topic
KW - Databases, Factual
KW - Europe
KW - Humans
KW - Multicenter Studies as Topic
KW - Nuclear Medicine
KW - Quality Control
KW - Reference Standards
KW - Tomography, Emission-Computed, Single-Photon
KW - Tropanes
U2 - 10.1007/s00259-011-1884-z
DO - 10.1007/s00259-011-1884-z
M3 - Journal article
C2 - 22089660
SN - 1619-7070
VL - 39
SP - 188
EP - 197
JO - European Journal of Nuclear Medicine and Molecular Imaging
JF - European Journal of Nuclear Medicine and Molecular Imaging
IS - 1
ER -