Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Prolapse reduction deteriorates the urethral closure mechanism

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Surgical treatment of primary uterine prolapse: a comparison of vaginal native tissue surgical techniques

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Comments on Letter to the Editor: prolapse reduction deteriorates the urethral closure mechanism

    Research output: Contribution to journalComment/debateResearchpeer-review

  3. A Danish national population-based cohort study of synthetic midurethral slings, 2007-2011

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Continuous vs stepwise anal acoustic reflectometry: An improved technique for physiological measurement of anal sphincter function?

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Native tissue repair is cost-effective in primary anterior POP

    Research output: Contribution to journalComment/debateResearchpeer-review

  3. Operativ behandling afhænger af postnummeret: Hvor er de videnskabelige selskaber og Sundhedsstyrelsen?

    Research output: Contribution to journalComment/debateCommunication

  4. Surgical treatment of primary uterine prolapse: a comparison of vaginal native tissue surgical techniques

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

INTRODUCTION AND HYPOTHESIS: Pelvic organ prolapse (POP) reduction is often performed in the preoperative assessment of women before POP surgery. Using urethral pressure reflectometry (UPR), we sought to investigate how POP reduction affects the urethral closure mechanism.

METHODS: Women with anterior or posterior vaginal wall prolapse stage ≥II with and without POP reduction were examined with a speculum. We performed prolapse staging according to the Pelvic Organ Prolapse Quantification system, UPR measurements at rest and during squeezing, and standardized stress tests with 300 ml saline. All examinations were repeated after insertion of a speculum.

RESULTS: We included 38 women: 22 with anterior and 16 with posterior vaginal wall prolapse POP-Q stage  ≥II. During POP reduction, resting and squeezing urethral pressures decreased by 2.5 cmH2O (p = 0.007) and 5.1 cmH2O (p < 0.0001), respectively, in all women. During POP reduction, the number of positive stress tests increased from four (18%) to eight (36%) in women with anterior vaginal wall prolapse and from one (6%) to nine (56%) in women with posterior vaginal wall prolapse.

CONCLUSIONS: POP reduction decreases urethral pressure, especially during squeezing, and consequently increases the number of positive stress tests. The test itself artificially deteriorates the urethral closure mechanism.

Original languageEnglish
JournalInternational Urogynecology Journal
Volume30
Issue number3
Pages (from-to)489-493
Number of pages5
ISSN0937-3462
DOIs
Publication statusPublished - Mar 2019

    Research areas

  • Female, Gynecological Examination, Humans, Middle Aged, Pelvic Organ Prolapse/complications, Pressure, Urethra/physiopathology, Urinary Incontinence, Stress/etiology, Urodynamics

ID: 59181264