Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Prognostic value of right ventricular echocardiographic measures in patients with heart failure with reduced ejection fraction

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. The AFSUMB Consensus Statements and Recommendations for the Clinical Practice of Contrast-Enhanced Ultrasound using Sonazoid

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Comment on "Intrauterine diagnosis and management of fetal goiter: a case report"

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Intrauterine Diagnosis and Management of Fetal Goiter: A Case Report

    Research output: Contribution to journalLetterResearchpeer-review

  4. A Doppler waveform index to characterize hepatic vein velocity pattern and evaluate hepatic fibrosis

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Frequency of Electrocardiographic Alterations and Pericardial Effusion in Patients With Uncomplicated Malaria

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Lung Ultrasound Findings Associated With COVID-19 ARDS, ICU Admission, and All-Cause Mortality

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Changes in left atrial structure and function over a decade in the general population

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Left atrial strain predicts incident atrial fibrillation in the general population: the Copenhagen City Heart Study

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

PURPOSE: Right ventricular (RV) dysfunction is associated with poor outcome in patients with heart failure. In order to better predict mortality in this patient group we wanted to compare the prognostic value of conventional and advanced RV echocardiographic measures.

METHODS: Echocardiographic examinations were retrieved from 701 patients. End point was all-cause mortality and follow-up 100%. RV parameters were measured offline in accordance with current guidelines. Speckle tracking was derived using the algorithm originally designed for the left ventricle.

RESULTS: During follow-up (median: 39 months) 118 patients (16.8%) died. RV global longitudinal strain (GLS) and RV free wall strain (FWS) remained associated with mortality after multivariable adjustment independent of Tricuspid annular plane systolic excursion (TAPSE) (RV GLS: HR 1.07, 95%CI 1.02-1.13, p = 0.010, per 1% decrease) (RV FWS: HR 1.05, 95%CI 1.01-1.09, p = 0.010, per 1% decrease). This seemed to be caused by significant associations in men. All RV estimates provided prognostic information incremental to established risk factors and significantly increased C-statistics.

CONCLUSIONS: RV GLS and FWS were associated with mortality in HFrEF patients after multivariable adjustment independent of TAPSE. TAPSE, however, remained as the strongest prognosticator in women. More research is needed to identify whether speckle tracking could be superior to conventional RV measures in identifying HFrEF patients with poor outcome.

Original languageEnglish
JournalJournal of clinical ultrasound : JCU
Volume49
Issue number9
Pages (from-to)903-913
Number of pages11
ISSN0091-2751
DOIs
Publication statusPublished - Nov 2021

Bibliographical note

© 2021 Wiley Periodicals LLC.

    Research areas

  • Echocardiography, Female, Heart Failure/diagnostic imaging, Heart Ventricles/diagnostic imaging, Humans, Male, Predictive Value of Tests, Prognosis, Stroke Volume, Ventricular Dysfunction, Right/diagnostic imaging, Ventricular Function, Right, speckle tracking, heart failure, echocardiography, 2DSTE, right ventricle

ID: 68905733