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Prognostic scoring models in parotid gland carcinoma

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Harvard

Westergaard-Nielsen, M, Möller, S, Godballe, C, Grau Eriksen, J, Larsen, SR, Kiss, K, Agander, T, Parm Ulhøi, B, Charabi, B, Ehlers Klug, T, Jacobsen, H, Johansen, J, Kristensen, CA, Andersen, E, Andersen, M & Bjørndal, K 2021, 'Prognostic scoring models in parotid gland carcinoma', Head and Neck, vol. 43, no. 7, pp. 2081-2090. https://doi.org/10.1002/hed.26672

APA

Westergaard-Nielsen, M., Möller, S., Godballe, C., Grau Eriksen, J., Larsen, S. R., Kiss, K., Agander, T., Parm Ulhøi, B., Charabi, B., Ehlers Klug, T., Jacobsen, H., Johansen, J., Kristensen, C. A., Andersen, E., Andersen, M., & Bjørndal, K. (2021). Prognostic scoring models in parotid gland carcinoma. Head and Neck, 43(7), 2081-2090. https://doi.org/10.1002/hed.26672

CBE

Westergaard-Nielsen M, Möller S, Godballe C, Grau Eriksen J, Larsen SR, Kiss K, Agander T, Parm Ulhøi B, Charabi B, Ehlers Klug T, Jacobsen H, Johansen J, Kristensen CA, Andersen E, Andersen M, Bjørndal K. 2021. Prognostic scoring models in parotid gland carcinoma. Head and Neck. 43(7):2081-2090. https://doi.org/10.1002/hed.26672

MLA

Vancouver

Westergaard-Nielsen M, Möller S, Godballe C, Grau Eriksen J, Larsen SR, Kiss K et al. Prognostic scoring models in parotid gland carcinoma. Head and Neck. 2021 Jul;43(7):2081-2090. https://doi.org/10.1002/hed.26672

Author

Westergaard-Nielsen, Marie ; Möller, Sören ; Godballe, Christian ; Grau Eriksen, Jesper ; Larsen, Stine Rosenkilde ; Kiss, Katalin ; Agander, Tina ; Parm Ulhøi, Benedicte ; Charabi, Birgitte ; Ehlers Klug, Tejs ; Jacobsen, Henrik ; Johansen, Jørgen ; Kristensen, Claus Andrup ; Andersen, Elo ; Andersen, Maria ; Bjørndal, Kristine. / Prognostic scoring models in parotid gland carcinoma. In: Head and Neck. 2021 ; Vol. 43, No. 7. pp. 2081-2090.

Bibtex

@article{8fbad3a9d6f4478ab70495aba561f07b,
title = "Prognostic scoring models in parotid gland carcinoma",
abstract = "BACKGROUND: The aim was to identify prognostic factors and test three prognostic scoring models that predicted the risk of recurrence in patients with parotid gland carcinoma.METHODS: All Danish patients with parotid gland carcinoma, treated with curative intent, from 1990 to 2015 (n = 726) were included. Potential prognostic factors were evaluated using Cox regression and competing risk analyses. The concordance of each prognostic model was estimated using Harrel's C index.RESULTS: The study population consisted of 344 men and 382 women, with a median age of 63 years. Age above 60 years, high grade histology, T3/T4 tumor, regional lymph node metastases, and involved surgical margins were all associated with a significant reduction in recurrence-free survival. The prognostic model that agreed best with actual outcomes had a C-index of 0.76.CONCLUSION: Prognostic scoring models may improve individualized follow-up strategies after curatively intended treatment for patients with parotid gland carcinoma.",
keywords = "follow-up, parotid gland carcinoma, prognosis, prognostic scoring model, recurrence risk",
author = "Marie Westergaard-Nielsen and S{\"o}ren M{\"o}ller and Christian Godballe and {Grau Eriksen}, Jesper and Larsen, {Stine Rosenkilde} and Katalin Kiss and Tina Agander and {Parm Ulh{\o}i}, Benedicte and Birgitte Charabi and {Ehlers Klug}, Tejs and Henrik Jacobsen and J{\o}rgen Johansen and Kristensen, {Claus Andrup} and Elo Andersen and Maria Andersen and Kristine Bj{\o}rndal",
note = "{\textcopyright} 2021 Wiley Periodicals LLC.",
year = "2021",
month = jul,
doi = "10.1002/hed.26672",
language = "English",
volume = "43",
pages = "2081--2090",
journal = "Head and Neck",
issn = "1043-3074",
publisher = "John/Wiley & Sons, Inc. John/Wiley & Sons Ltd",
number = "7",

}

RIS

TY - JOUR

T1 - Prognostic scoring models in parotid gland carcinoma

AU - Westergaard-Nielsen, Marie

AU - Möller, Sören

AU - Godballe, Christian

AU - Grau Eriksen, Jesper

AU - Larsen, Stine Rosenkilde

AU - Kiss, Katalin

AU - Agander, Tina

AU - Parm Ulhøi, Benedicte

AU - Charabi, Birgitte

AU - Ehlers Klug, Tejs

AU - Jacobsen, Henrik

AU - Johansen, Jørgen

AU - Kristensen, Claus Andrup

AU - Andersen, Elo

AU - Andersen, Maria

AU - Bjørndal, Kristine

N1 - © 2021 Wiley Periodicals LLC.

PY - 2021/7

Y1 - 2021/7

N2 - BACKGROUND: The aim was to identify prognostic factors and test three prognostic scoring models that predicted the risk of recurrence in patients with parotid gland carcinoma.METHODS: All Danish patients with parotid gland carcinoma, treated with curative intent, from 1990 to 2015 (n = 726) were included. Potential prognostic factors were evaluated using Cox regression and competing risk analyses. The concordance of each prognostic model was estimated using Harrel's C index.RESULTS: The study population consisted of 344 men and 382 women, with a median age of 63 years. Age above 60 years, high grade histology, T3/T4 tumor, regional lymph node metastases, and involved surgical margins were all associated with a significant reduction in recurrence-free survival. The prognostic model that agreed best with actual outcomes had a C-index of 0.76.CONCLUSION: Prognostic scoring models may improve individualized follow-up strategies after curatively intended treatment for patients with parotid gland carcinoma.

AB - BACKGROUND: The aim was to identify prognostic factors and test three prognostic scoring models that predicted the risk of recurrence in patients with parotid gland carcinoma.METHODS: All Danish patients with parotid gland carcinoma, treated with curative intent, from 1990 to 2015 (n = 726) were included. Potential prognostic factors were evaluated using Cox regression and competing risk analyses. The concordance of each prognostic model was estimated using Harrel's C index.RESULTS: The study population consisted of 344 men and 382 women, with a median age of 63 years. Age above 60 years, high grade histology, T3/T4 tumor, regional lymph node metastases, and involved surgical margins were all associated with a significant reduction in recurrence-free survival. The prognostic model that agreed best with actual outcomes had a C-index of 0.76.CONCLUSION: Prognostic scoring models may improve individualized follow-up strategies after curatively intended treatment for patients with parotid gland carcinoma.

KW - follow-up

KW - parotid gland carcinoma

KW - prognosis

KW - prognostic scoring model

KW - recurrence risk

UR - http://www.scopus.com/inward/record.url?scp=85102637813&partnerID=8YFLogxK

U2 - 10.1002/hed.26672

DO - 10.1002/hed.26672

M3 - Journal article

C2 - 33734517

VL - 43

SP - 2081

EP - 2090

JO - Head and Neck

JF - Head and Neck

SN - 1043-3074

IS - 7

ER -

ID: 64640044