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Proghrelin peptides: Desacyl ghrelin is a powerful inhibitor of acylated ghrelin, likely to impair physiological effects of acyl ghrelin but not of obestatin A study of pancreatic polypeptide secretion from mouse islets

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@article{7a63364c3c164d2eb2a0816a5d6fd454,
title = "Proghrelin peptides: Desacyl ghrelin is a powerful inhibitor of acylated ghrelin, likely to impair physiological effects of acyl ghrelin but not of obestatin A study of pancreatic polypeptide secretion from mouse islets",
abstract = "Proghrelin, produced by the ghrelin (A-like) cells of the gastric mucosa, gives rise to cleavage products, including desacyl ghrelin, acyl ghrelin and obestatin. The products are thought to be secreted concomitantly. In an earlier study we found acyl ghrelin and obestatin, but not desacyl ghrelin, to suppress the release of hormones from isolated islets of mouse and rat pancreas.",
author = "Rajesh Kumar and Albert Salehi and Rehfeld, {Jens F} and Peter H{\"o}glund and Erik Lindstr{\"o}m and Rolf H{\aa}kanson",
note = "Copyright 2010 Elsevier B.V. All rights reserved.",
year = "2010",
month = "9",
day = "24",
doi = "10.1016/j.regpep.2010.06.005",
language = "English",
volume = "164",
pages = "65--70",
journal = "Regulatory Peptides",
issn = "0167-0115",
publisher = "Elsevier BV",
number = "2-3",

}

RIS

TY - JOUR

T1 - Proghrelin peptides: Desacyl ghrelin is a powerful inhibitor of acylated ghrelin, likely to impair physiological effects of acyl ghrelin but not of obestatin A study of pancreatic polypeptide secretion from mouse islets

AU - Kumar, Rajesh

AU - Salehi, Albert

AU - Rehfeld, Jens F

AU - Höglund, Peter

AU - Lindström, Erik

AU - Håkanson, Rolf

N1 - Copyright 2010 Elsevier B.V. All rights reserved.

PY - 2010/9/24

Y1 - 2010/9/24

N2 - Proghrelin, produced by the ghrelin (A-like) cells of the gastric mucosa, gives rise to cleavage products, including desacyl ghrelin, acyl ghrelin and obestatin. The products are thought to be secreted concomitantly. In an earlier study we found acyl ghrelin and obestatin, but not desacyl ghrelin, to suppress the release of hormones from isolated islets of mouse and rat pancreas.

AB - Proghrelin, produced by the ghrelin (A-like) cells of the gastric mucosa, gives rise to cleavage products, including desacyl ghrelin, acyl ghrelin and obestatin. The products are thought to be secreted concomitantly. In an earlier study we found acyl ghrelin and obestatin, but not desacyl ghrelin, to suppress the release of hormones from isolated islets of mouse and rat pancreas.

U2 - 10.1016/j.regpep.2010.06.005

DO - 10.1016/j.regpep.2010.06.005

M3 - Journal article

VL - 164

SP - 65

EP - 70

JO - Regulatory Peptides

JF - Regulatory Peptides

SN - 0167-0115

IS - 2-3

ER -

ID: 31046564