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Proghrelin peptides: Desacyl ghrelin is a powerful inhibitor of acylated ghrelin, likely to impair physiological effects of acyl ghrelin but not of obestatin A study of pancreatic polypeptide secretion from mouse islets

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  1. Gene expression profiling of gastric mucosa in mice lacking CCK and gastrin receptors

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  2. Natriuretic peptides and cerebral hemodynamics

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  3. Adropin: a new regulatory peptide in cardiovascular endocrinology

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  4. Cardiac C-type natriuretic peptide gene expression and plasma concentrations in neonatal piglets

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  5. Gut hormones - Team workers or solo trippers?

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  1. Oral D/L-3-Hydroxybutyrate stimulates cholecystokinin and insulin secretion and slows gastric emptying in healthy males

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  2. Bilio-enteric flow and plasma concentrations of bile acids after gastric bypass and sleeve gastrectomy

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  3. Circadian variations in plasma concentrations of cholecystokinin and gastrin in man

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  4. Increased oral sodium chloride intake in humans amplifies selectively postprandial GLP-1 but not GIP, CCK, and gastrin in plasma

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  • Rajesh Kumar
  • Albert Salehi
  • Jens F Rehfeld
  • Peter Höglund
  • Erik Lindström
  • Rolf Håkanson
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Proghrelin, produced by the ghrelin (A-like) cells of the gastric mucosa, gives rise to cleavage products, including desacyl ghrelin, acyl ghrelin and obestatin. The products are thought to be secreted concomitantly. In an earlier study we found acyl ghrelin and obestatin, but not desacyl ghrelin, to suppress the release of hormones from isolated islets of mouse and rat pancreas.
Original languageEnglish
JournalRegulatory Peptides
Volume164
Issue number2-3
Pages (from-to)65-70
Number of pages6
ISSN0167-0115
DOIs
Publication statusPublished - 24 Sep 2010

ID: 31046564