Pro-inflammatory cytokine treatment of human islets is permissive for gasdermin D-mediated pyroptosis by toll-like receptor 4 and inflammasome activators

Fumie Mitani; Kristine Henriksen; Cecilie Amalie Søndergaard Svane; Anne Jørgensen; Simranjeet  Kaur; Caroline Frørup; Joachim Størling

doi:10.1007/s00125-025-06497-1

Pro-inflammatory cytokine treatment of human islets is permissive for gasdermin D-mediated pyroptosis by toll-like receptor 4 and inflammasome activators

Fumie Mitani, Kristine Henriksen, Cecilie Amalie Søndergaard Svane, Anne Jørgensen, Simranjeet Kaur, Caroline Frørup, Joachim Størling

Steno Diabetes Center Copenhagen

Original language	English
Article number	495
Journal	Diabetologia
Volume	68
Issue number	Suppl 1
Pages (from-to)	S257
ISSN	0012-186X
DOIs	https://doi.org/10.1007/s00125-025-06497-1
Publication status	Published - Oct 2025
Event	61th EASD Annual Meeting: EASD 2025 - Wien, Austria Duration: 15 Sept 2025 → 19 Sept 2025

Conference

Conference	61th EASD Annual Meeting: EASD 2025
Country/Territory	Austria
City	Wien
Period	15/09/2025 → 19/09/2025

Access to Document

10.1007/s00125-025-06497-1Licence: Unspecified

Cite this

Pro-inflammatory cytokine treatment of human islets is permissive for gasdermin D-mediated pyroptosis by toll-like receptor 4 and inflammasome activators. / Mitani, Fumie; Henriksen, Kristine ; Svane, Cecilie Amalie Søndergaard et al.
In: Diabetologia, Vol. 68, No. Suppl 1, 495, 10.2025, p. S257.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

@article{e07940378ff64fc1bb8a06f04b2e1e55,

title = "Pro-inflammatory cytokine treatment of human islets is permissive for gasdermin D-mediated pyroptosis by toll-like receptor 4 and inflammasome activators",

author = "Fumie Mitani and Kristine Henriksen and Svane, \{Cecilie Amalie S{\o}ndergaard\} and Anne J{\o}rgensen and Simranjeet Kaur and Caroline Fr{\o}rup and Joachim St{\o}rling",

year = "2025",

month = oct,

doi = "10.1007/s00125-025-06497-1",

language = "English",

volume = "68",

pages = "S257",

journal = "Diabetologia",

issn = "0012-186X",

publisher = "Springer Science and Business Media Deutschland GmbH",

number = "Suppl 1",

note = "61th EASD Annual Meeting: EASD 2025, EASD ; Conference date: 15-09-2025 Through 19-09-2025",

}

TY - ABST

T1 - Pro-inflammatory cytokine treatment of human islets is permissive for gasdermin D-mediated pyroptosis by toll-like receptor 4 and inflammasome activators

AU - Mitani, Fumie

AU - Henriksen, Kristine

AU - Svane, Cecilie Amalie Søndergaard

AU - Jørgensen, Anne

AU - Kaur, Simranjeet

AU - Frørup, Caroline

AU - Størling, Joachim

PY - 2025/10

Y1 - 2025/10

U2 - 10.1007/s00125-025-06497-1

DO - 10.1007/s00125-025-06497-1

M3 - Conference abstract in journal

SN - 0012-186X

VL - 68

SP - S257

JO - Diabetologia

JF - Diabetologia

IS - Suppl 1

M1 - 495

T2 - 61th EASD Annual Meeting: EASD 2025

Y2 - 15 September 2025 through 19 September 2025

ER -