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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Primary prevention of fat and weight gain among obesity susceptible healthy weight preschool children. Main results from the "Healthy Start" randomized controlled intervention

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DOI

  1. Nighttime sleep duration trajectories were associated with body mass index trajectories in early childhood

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  2. Body mass index trajectories from 2 to 18 years - exploring differences between European cohorts

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  3. No influence of sugar, snacks and fast food intake on the degree of obesity or treatment effect in childhood obesity

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  1. Phase angle measured by bioelectrical impedance analysis and the risk of cardiovascular disease among adult Danes

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  2. Protein Intake During Infancy and Subsequent Body Mass Index in Early Childhood: Results from the Melbourne InFANT Program

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  3. Loss of height predicts total and cardiovascular mortality: a cohort study of northern European women

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BACKGROUND: A vital public health challenge lies in understanding the primary drivers behind excessive weight gain among healthy weight individuals.

OBJECTIVES: To examine if excessive weight and fat gain can be prevented among healthy weight, obesity susceptible children aged 2 to 6 years.

METHODS: Eligible children were identified based on information on either a high birth weight, maternal pre-pregnancy obesity or maternal low educational level from national registries, and randomized into an intervention group, a control group and a shadow control group. All children with overweight at baseline were excluded from subsequent analysis (n = 196), while healthy weight children were included (n = 926). The intervention was designed to deliver improvements in diet and physical activity habits, optimization of sleep quantity and quality, and reduction of family stress. The average intervention period was 1.3 years.

RESULTS: Intention-to-treat analyses indicated a lower gain in percentage fat mass and a higher gain in fat-free mass in the intervention group compared with the control group. However, the results should be interpreted with caution, as they were clinically small and borderline significant, only.

CONCLUSION: This primary prevention intervention among young healthy weight children with susceptibility to future obesity had clinically small effects on growth and body composition. More interventions, conducting primary obesity prevention, are urgently needed.

Original languageEnglish
Article numbere12736
JournalPediatric obesity
Volume16
Issue number4
Pages (from-to)e12736
ISSN1524-6817
DOIs
Publication statusPublished - Apr 2021

    Research areas

  • children, intervention, obesity, primary prevention, susceptibility

ID: 67552226