Primary localized amyloidosis in nasopharynx and oropharynx

Primary localized amyloidosis (PLA) is a rare benign disease defined by the presence of extracellular deposits of insoluble amyloid fibrils without systemic involvement. We report a case story of a patient with a tumour in pharynx. It was excised and based on histopathology the diagnosis PLA was confirmed. The patient was examined for systemic amyloidosis (SA). All tests were normal except for an elevated lactate dehydrogenase level. Using PET/CT we found a hypermetabolic lymph node, but the ultrasound examination was normal. The patient continued follow-up and has so far no sign of recurrence of SA.