Abstract
An accidental transfusion of hepatitis B surface antigen (HBsAg) and hepatitis B e antigen (HBeAg) positive whole blood was given to a 19-yr-old male, bleeding after tonsillectomy. Serum obtained from the patient before the transfusion revealed no hepatitis B antigens or antibodies. After the transfusion the patient became HBsAg-positive, cleared this antigen and developed antibodies to both HBsAg and HBeAg. The transfusion blood was positive for total antibody and IgM antibody to hepatitis B core antigen (HBcAg). The patient's blood became positive for these antibodies after the transfusion, but with declining titres. Liver tests were normal through the entire follow-up. The serological and clinical course suggests immunisation to passively transferred antigens without hepatitis.
Original language | English |
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Journal | Scandinavian Journal of Infectious Diseases |
Volume | 15 |
Issue number | 4 |
Pages (from-to) | 399-401 |
Number of pages | 3 |
ISSN | 0036-5548 |
Publication status | Published - 1983 |
Keywords
- Adult
- Blood Transfusion
- Hemorrhage
- Hepatitis B Antigens
- Hepatitis B Surface Antigens
- Hepatitis B e Antigens
- Humans
- Immunization, Passive
- Male
- Postoperative Complications
- Tonsillectomy