Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Prevalence of chronic wounds in the general population: systematic review and meta-analysis of observational studies

Research output: Contribution to journalJournal articleResearchpeer-review

  1. The role of body mass index in incidence and persistence of cervical human papillomavirus infection

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Fever in pregnancy and offspring head circumference

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. No impact of surgery on cognitive function: a longitudinal study of middle-aged Danish twins

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. No changes in serum tryptase after bariatric surgery

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Does liver damage explain the inverse association between vitamin D status and mortality?

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Concentration- and pH-Dependent Oligomerization of the Thrombin-Derived C-Terminal Peptide TCP-25

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Thrombin-derived C-terminal fragments aggregate and scavenge bacteria and their proinflammatory products

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. A C-terminal peptide of TFPI-1 facilitates cytosolic delivery of nucleic acid cargo into mammalian cells

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. A dual-action peptide-containing hydrogel targets wound infection and inflammation

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Degradable dendritic nanogels as carriers for antimicrobial peptides

    Research output: Contribution to journalJournal articleResearchpeer-review

  • Laura Martinengo
  • Maja Olsson
  • Ram Bajpai
  • Michael Soljak
  • Zee Upton
  • Artur Schmidtchen
  • Josip Car
  • Krister Järbrink
View graph of relations

PURPOSE: Chronic wounds are a major public health challenge, but little is known about the true burden with studies reporting different estimates because of disparities in study designs and measurement methods. This hampers efficient resource allocation, planning, and improvement of wound care.

METHODS: Our study aimed to pool prevalence estimates from a global perspective by systematically carrying out searches in MEDLINE, EMBASE, Cochrane, CINAHL, Global Health, and PsycINFO databases for articles reporting the prevalence of chronic wounds in adults, from January 2000 to June 2018. The included publications had to define wound chronicity by duration (≥3 weeks), and/or labeling the wounds as chronic, complex, or hard-to-heal.

RESULTS: Seventeen studies met the inclusion criteria, and 11 studies analyzing chronic wounds in the general population were included in random effects meta-analyses to calculate pooled prevalence. Chronic wounds of mixed etiologies (n = 3) showed a pooled prevalence of 2.21 per 1000 population, and for chronic leg ulcers (n = 9), the prevalence was estimated at 1.51 per 1000 population.

CONCLUSIONS: Our findings, aligned to previous studies reporting point prevalence of chronic wounds identified within the healthcare system, showed that the vast majority of chronic wounds in epidemiological studies are made up by chronic leg ulcers.

Original languageEnglish
JournalAnnals of Epidemiology
Volume29
Pages (from-to)8-15
Number of pages8
ISSN1047-2797
DOIs
Publication statusPublished - Jan 2019

    Research areas

  • Aged, Aged, 80 and over, Chronic Disease/epidemiology, Female, Humans, Male, Middle Aged, Observational Studies as Topic, Prevalence, Treatment Outcome, Wound Healing, Wounds and Injuries/epidemiology

ID: 58974486