Prevalence of anxiety and depression symptoms in pregnant women with type 2 diabetes and the impact on glycaemic control

Björg Ásbjörnsdóttir, Marianne Vestgaard, Nicoline C Do, Lene Ringholm, Lise L T Andersen, Dorte M Jensen, Peter Damm, Elisabeth R Mathiesen

    12 Citations (Scopus)

    Abstract

    AIMS: To study the prevalence of anxiety and depression symptoms in pregnant women with type 2 diabetes compared with pregnant women without diabetes. Secondly, to explore whether anxiety and/or depression symptoms in early pregnancy have an impact on glycaemic control and gestational weight gain.

    METHODS: A prospective cohort study of 90 consecutive singleton pregnant women with type 2 diabetes and 88 singleton pregnant women without diabetes. All women completed the Hospital Anxiety and Depression Scale questionnaire in early and late pregnancy. A score ≥8 in the anxiety or the depression scale was used to define anxiety and/or depression symptoms.

    RESULTS: Anxiety and/or depression symptoms were present in 40% of women with type 2 diabetes and 7% of women without diabetes in early pregnancy (Relative Risk=5.87 (95% Confidence Interval: 2.60-13.22). The figures were similar in late pregnancy. In women with type 2 diabetes and anxiety and/or depression symptoms in early pregnancy, HbA1c (mean±SD) was 52±14 vs. 49±11 mmol/mol (6.9±1.2 vs. 6.6±1.0%), p=0.31 in early pregnancy and 43±8 vs. 40±4 mmol/mol (6.1±0.7 vs. 5.8±0.4%), p=0.04 in late pregnancy compared with women without symptoms. Gestational weight gain was similar in both groups.

    CONCLUSIONS: In women with type 2 diabetes, 40% had anxiety and/or depression symptoms in early pregnancy. Women with these symptoms obtained less optimal glycaemic control in late pregnancy but similar gestational weight gain as the remaining women.

    Original languageEnglish
    Article numbere14506
    JournalDiabetic Medicine
    Volume38
    Issue number3
    Pages (from-to)e14506
    ISSN1464-5491
    DOIs
    Publication statusPublished - Mar 2021

    Keywords

    • Adult
    • Anxiety/epidemiology
    • Case-Control Studies
    • Cohort Studies
    • Denmark/epidemiology
    • Depression/epidemiology
    • Diabetes Mellitus, Type 2/blood
    • Female
    • Gestational Weight Gain/physiology
    • Glycated Hemoglobin A/analysis
    • Glycemic Control/psychology
    • Humans
    • Pregnancy
    • Pregnancy in Diabetics/blood
    • Prevalence

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