Abstract
AIMS: To study the prevalence of anxiety and depression symptoms in pregnant women with type 2 diabetes compared with pregnant women without diabetes. Secondly, to explore whether anxiety and/or depression symptoms in early pregnancy have an impact on glycaemic control and gestational weight gain.
METHODS: A prospective cohort study of 90 consecutive singleton pregnant women with type 2 diabetes and 88 singleton pregnant women without diabetes. All women completed the Hospital Anxiety and Depression Scale questionnaire in early and late pregnancy. A score ≥8 in the anxiety or the depression scale was used to define anxiety and/or depression symptoms.
RESULTS: Anxiety and/or depression symptoms were present in 40% of women with type 2 diabetes and 7% of women without diabetes in early pregnancy (Relative Risk=5.87 (95% Confidence Interval: 2.60-13.22). The figures were similar in late pregnancy. In women with type 2 diabetes and anxiety and/or depression symptoms in early pregnancy, HbA1c (mean±SD) was 52±14 vs. 49±11 mmol/mol (6.9±1.2 vs. 6.6±1.0%), p=0.31 in early pregnancy and 43±8 vs. 40±4 mmol/mol (6.1±0.7 vs. 5.8±0.4%), p=0.04 in late pregnancy compared with women without symptoms. Gestational weight gain was similar in both groups.
CONCLUSIONS: In women with type 2 diabetes, 40% had anxiety and/or depression symptoms in early pregnancy. Women with these symptoms obtained less optimal glycaemic control in late pregnancy but similar gestational weight gain as the remaining women.
Original language | English |
---|---|
Article number | e14506 |
Journal | Diabetic Medicine |
Volume | 38 |
Issue number | 3 |
Pages (from-to) | e14506 |
ISSN | 1464-5491 |
DOIs | |
Publication status | Published - Mar 2021 |
Keywords
- Adult
- Anxiety/epidemiology
- Case-Control Studies
- Cohort Studies
- Denmark/epidemiology
- Depression/epidemiology
- Diabetes Mellitus, Type 2/blood
- Female
- Gestational Weight Gain/physiology
- Glycated Hemoglobin A/analysis
- Glycemic Control/psychology
- Humans
- Pregnancy
- Pregnancy in Diabetics/blood
- Prevalence