TY - JOUR
T1 - Prevalence and characteristics of drug-drug interactions among hospitalised patients in the Capital Region of Denmark
AU - Pedersen, Hans Kristian Råket
AU - Sørensen, Anne Mette Skov
AU - Schelde, Astrid Blicher
AU - Nyeland, Martin Erik
AU - Jimenez Solem, Espen
PY - 2021/10/1
Y1 - 2021/10/1
N2 - Previous studies on the prevalence of drug-drug interactions (DDIs) have largely been restricted to specific hospital departments. We identified common drug combinations and potential drug-drug interactions (pDDIs) in an entire hospital population throughout 1 year. Frequently administered drug combinations involved analgesics, cardiovascular medicines and gastrointestinal medicines. The prevalence of pDDIs among newly hospitalised patients was 2.6%. The most common pDDIs were ibuprofen–paracetamol, pantoprazole–paracetamol and morphine–paracetamol. Critical pDDIs were rare and only accounted for 0.4% of pDDIs.
AB - Previous studies on the prevalence of drug-drug interactions (DDIs) have largely been restricted to specific hospital departments. We identified common drug combinations and potential drug-drug interactions (pDDIs) in an entire hospital population throughout 1 year. Frequently administered drug combinations involved analgesics, cardiovascular medicines and gastrointestinal medicines. The prevalence of pDDIs among newly hospitalised patients was 2.6%. The most common pDDIs were ibuprofen–paracetamol, pantoprazole–paracetamol and morphine–paracetamol. Critical pDDIs were rare and only accounted for 0.4% of pDDIs.
M3 - Journal article
VL - 330
SP - 1279
EP - 1282
JO - Adverse Drug Reaction Bulletin
JF - Adverse Drug Reaction Bulletin
SN - 0044-6394
IS - 1
ER -