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Preoperative plasma TIMP-1 is an independent prognostic indicator in patients with primary colorectal cancer: a prospective validation study

Helgi Birgisson, Hans J Nielsen, Ib Jarle Christensen, Bengt Glimelius, Nils Brünner

48 Citations (Scopus)

Abstract

Previous studies have suggested plasma tissue inhibitor of metalloproteinases-1 (TIMP-1) as a stage independent prognostic marker in colorectal cancer (CRC) patients. The aim was to validate plasma TIMP-1 and serum carcino-embryonic antigen (CEA) levels as prognostic indicators in an independent population-based cohort of patients with CRC.
Original languageEnglish
JournalEuropean journal of cancer (Oxford, England : 1990)
Volume46
Issue number18
Pages (from-to)3323-31
Number of pages9
DOIs
Publication statusPublished - 1 Dec 2010

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