Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
E-pub ahead of print

Preoperative endoscopic retrograde cholangio-pancreatography (ERCP) is a risk factor for surgical site infections after laparoscopic cholecystectomy

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Risk of adhesive bowel obstruction after abdominal surgery. A national cohort study of 665,423 Danish women

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Cervical spinal cord injury after blunt assault: Just a pain in the neck?

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Ventral hernia and pregnancy: A systematic review

    Research output: Contribution to journalReviewResearchpeer-review

  4. Single-incision laparoscopy versus standard laparoscopy for colorectal surgery: A systematic review and meta-analysis

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Operating at night does not increase the risk of intraoperative adverse events

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Cervical spinal cord injury after blunt assault: Just a pain in the neck?

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Ketamine as a Rapid Sequence Induction Agent in the Trauma Population: A Systematic Review

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Supplemental oxygen and hyperoxemia in trauma patients: A prospective, observational study

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Initial use of supplementary oxygen for trauma patients: a systematic review

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Operating at night does not increase the risk of intraoperative adverse events

    Research output: Contribution to journalJournal articleResearchpeer-review

  • Thomas Peponis
  • Nikhil Panda
  • Trine G Eskesen
  • David G Forcione
  • Dante D Yeh
  • Noelle Saillant
  • Haytham M A Kaafarani
  • David R King
  • Marc A de Moya
  • George C Velmahos
  • Peter J Fagenholz
View graph of relations

BACKGROUND: We sought to examine whether preoperative endoscopic retrograde cholangio-pancreatography (ERCP) increases the risk of surgical site infections (SSI) after laparoscopic cholecystectomy.

METHODS: Patients admitted to an academic hospital from 2010 to 2016, who were older than 18 and had a laparoscopic or a laparoscopic converted to open cholecystectomy for complicated biliary tract disease were included. We compared those who had a preoperative ERCP to those who did not. Our primary endpoint was the rate of SSI.

RESULTS: A total of 640 patients were included. Of them, 122 (19.1%) received preoperative ERCP and 518 (80.9%) did not. The former had different preoperative diagnoses compared to non-ERCP patients (choledocholithiasis [35.2%-7.0%], acute cholecystitis [31.2%-76.4%], gallstone pancreatitis [20.5%-16.2%], and cholangitis [13.1%-0.4%], p < 0.001). The rate of SSI was higher in the preoperative ERCP group (11.5%-4.0%, p = 0.005). In a multivariable analysis conversion to open (OR = 2.57, 95% CI = 1.06-6.21, p = 0.037) and preoperative ERCP (OR = 3.12, 95% CI = 1.34-7.22, p = 0.008) were the only independent predictors of SSI.

CONCLUSION: Preoperative ERCP is associated with a threefold increase in the risk of SSI after laparoscopic cholecystectomy.

Original languageEnglish
JournalAmerican Journal of Surgery
ISSN0002-9610
DOIs
Publication statusE-pub ahead of print - 2019

    Research areas

  • Endoscopic retrograde cholangio-pancreatography, ERCP, Laparoscopic cholecystectomy, Surgical site infection

ID: 56967086