Prediction of severe adverse event from vital signs for post-operative patients

Ying Gu, Soren M Rasmussen, Jesper Molgaard, Camilla Haahr-Raunkjar, Christian S Meyhoff, Eske K Aasvang, Helge B D Sorensen


Monitoring post-operative patients is important for preventing severe adverse events (SAE), which increases morbidity and mortality. Conventional bedside monitoring system has demonstrated the difficulty in long term monitoring of those patients because majority of them are ambulatory. With development of wearable system and advanced data analytics, those patients would benefit greatly from continuous and predictive monitoring. In this study, we aim to predict SAE based on monitoring of vital signs. Heart rate, respiration rate, and blood oxygen saturation were continuously acquired by wearable devices and blood pressure was measured intermittently from 453 post-operative patients. SAEs from various complications were extracted from patients' database. The trends of vital signs were first extracted with moving average. Then four descriptive statistics were calculated from trend of each modality as features. Finally, a machine learning approach based on support vector machine was employed for prediction of SAE. It has shown the averaged accuracy of 89%, sensitivity of 80%, specificity of 93% and the area under receiver operating characteristic curve (AUROC) of 93%. These findings are promising and demonstrate the feasibility of predicting SAE from vital signs acquired with wearable devices and measured intermittently.

Original languageEnglish
JournalProceedings of the International Conference of the IEEE Engineering in Medicine and Biology Society
Pages (from-to)971-974
Number of pages4
Publication statusPublished - Nov 2021


  • Humans
  • Monitoring, Physiologic
  • Oxygen Saturation
  • Respiratory Rate
  • Vital Signs
  • Wearable Electronic Devices


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