Population pharmacokinetics of buprenorphine following a two-stage intravenous infusion in healthy volunteers

Mette L Jensen; David J R Foster; Richard N Upton; Kim Kristensen; Steen H Hansen; Niels-Henrik Jensen; Bettina N Nielsen; Ulrik Skram; Hanne H Villesen; Lona Louring Christrup

doi:10.1007/s00228-007-0377-2

Population pharmacokinetics of buprenorphine following a two-stage intravenous infusion in healthy volunteers

Mette L Jensen, David J R Foster, Richard N Upton, Kim Kristensen, Steen H Hansen, Niels-Henrik Jensen, Bettina N Nielsen, Ulrik Skram, Hanne H Villesen, Lona Louring Christrup

18 Citations (Scopus)

Abstract

The aim of this investigation was to characterize the pharmacokinetics of buprenorphine following administration of an intravenous (i.v.) infusion. To date, the population kinetics of buprenorphine has been described for bolus administration only.

Original language	English
Journal	European Journal of Clinical Pharmacology
Volume	63
Issue number	12
Pages (from-to)	1153-9
Number of pages	7
ISSN	0031-6970
DOIs	https://doi.org/10.1007/s00228-007-0377-2
Publication status	Published - 1 Dec 2007

Keywords

Adult
Analgesics, Opioid
Buprenorphine
Chromatography, High Pressure Liquid
Denmark
Humans
Infusions, Intravenous
Male
Models, Biological
Population Surveillance

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Jensen, M. L., Foster, D. J. R., Upton, R. N., Kristensen, K., Hansen, S. H., Jensen, N.-H., Nielsen, B. N., Skram, U., Villesen, H. H., & Christrup, L. L. (2007). Population pharmacokinetics of buprenorphine following a two-stage intravenous infusion in healthy volunteers. European Journal of Clinical Pharmacology, 63(12), 1153-9. https://doi.org/10.1007/s00228-007-0377-2

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AU - Jensen, Mette L

AU - Foster, David J R

AU - Upton, Richard N

AU - Kristensen, Kim

AU - Hansen, Steen H

AU - Jensen, Niels-Henrik

AU - Nielsen, Bettina N

AU - Skram, Ulrik

AU - Villesen, Hanne H

AU - Christrup, Lona Louring

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N2 - The aim of this investigation was to characterize the pharmacokinetics of buprenorphine following administration of an intravenous (i.v.) infusion. To date, the population kinetics of buprenorphine has been described for bolus administration only.

AB - The aim of this investigation was to characterize the pharmacokinetics of buprenorphine following administration of an intravenous (i.v.) infusion. To date, the population kinetics of buprenorphine has been described for bolus administration only.

KW - Adult

KW - Analgesics, Opioid

KW - Buprenorphine

KW - Chromatography, High Pressure Liquid

KW - Denmark

KW - Humans

KW - Infusions, Intravenous

KW - Male

KW - Models, Biological

KW - Population Surveillance

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M3 - Journal article

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JO - European Journal of Clinical Pharmacology

JF - European Journal of Clinical Pharmacology

IS - 12

ER -

Population pharmacokinetics of buprenorphine following a two-stage intravenous infusion in healthy volunteers

Abstract

Keywords

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