Pooled human platelet lysate versus fetal bovine serum-investigating the proliferation rate, chromosome stability and angiogenic potential of human adipose tissue-derived stem cells intended for clinical use

Stig-Frederik Trojahn Kølle; Roberto S Oliveri; Peter V Glovinski; Eva Maria Kirchhoff; Anders Bruun Mathiasen; Jens Jørgen Elberg; Peter Stemann Andersen; Krzysztof Tadeusz Drzewiecki; Anne Fischer-Nielsen

doi:10.1016/j.jcyt.2013.01.217

Pooled human platelet lysate versus fetal bovine serum-investigating the proliferation rate, chromosome stability and angiogenic potential of human adipose tissue-derived stem cells intended for clinical use

Stig-Frederik Trojahn Kølle, Roberto S Oliveri, Peter V Glovinski, Eva Maria Kirchhoff, Anders Bruun Mathiasen, Jens Jørgen Elberg, Peter Stemann Andersen, Krzysztof Tadeusz Drzewiecki, Anne Fischer-Nielsen

86 Citations (Scopus)

Abstract

Because of an increasing focus on the use of adipose-derived stem cells (ASCs) in clinical trials, the culture conditions for these cells are being optimized. We compared the proliferation rates and chromosomal stability of ASCs that had been cultured in Dulbecco's modified Eagle's Medium (DMEM) supplemented with either pooled human platelet lysate (pHPL) or clinical-grade fetal bovine serum (FBS) (DMEM(pHPL) versus DMEM(FBS)).

Original language	English
Journal	Cytotherapy
Volume	15
Issue number	9
Pages (from-to)	1086-97
Number of pages	12
ISSN	1465-3249
DOIs	https://doi.org/10.1016/j.jcyt.2013.01.217
Publication status	Published - Sept 2013

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Trojahn Kølle, S.-F., Oliveri, R. S., Glovinski, P. V., Kirchhoff, E. M., Mathiasen, A. B., Elberg, J. J., Andersen, P. S., Drzewiecki, K. T., & Fischer-Nielsen, A. (2013). Pooled human platelet lysate versus fetal bovine serum-investigating the proliferation rate, chromosome stability and angiogenic potential of human adipose tissue-derived stem cells intended for clinical use. Cytotherapy, 15(9), 1086-97. https://doi.org/10.1016/j.jcyt.2013.01.217

Pooled human platelet lysate versus fetal bovine serum-investigating the proliferation rate, chromosome stability and angiogenic potential of human adipose tissue-derived stem cells intended for clinical use. / Trojahn Kølle, Stig-Frederik; Oliveri, Roberto S; Glovinski, Peter V et al.
In: Cytotherapy, Vol. 15, No. 9, 09.2013, p. 1086-97.

Research output: Contribution to journal › Journal article › Research › peer-review

Trojahn Kølle, S-F, Oliveri, RS, Glovinski, PV , Kirchhoff, EM , Mathiasen, AB, Elberg, JJ, Andersen, PS, Drzewiecki, KT & Fischer-Nielsen, A 2013, 'Pooled human platelet lysate versus fetal bovine serum-investigating the proliferation rate, chromosome stability and angiogenic potential of human adipose tissue-derived stem cells intended for clinical use', Cytotherapy, vol. 15, no. 9, pp. 1086-97. https://doi.org/10.1016/j.jcyt.2013.01.217

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title = "Pooled human platelet lysate versus fetal bovine serum-investigating the proliferation rate, chromosome stability and angiogenic potential of human adipose tissue-derived stem cells intended for clinical use",

abstract = "Because of an increasing focus on the use of adipose-derived stem cells (ASCs) in clinical trials, the culture conditions for these cells are being optimized. We compared the proliferation rates and chromosomal stability of ASCs that had been cultured in Dulbecco's modified Eagle's Medium (DMEM) supplemented with either pooled human platelet lysate (pHPL) or clinical-grade fetal bovine serum (FBS) (DMEM(pHPL) versus DMEM(FBS)).",

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year = "2013",

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AU - Trojahn Kølle, Stig-Frederik

AU - Oliveri, Roberto S

AU - Glovinski, Peter V

AU - Kirchhoff, Eva Maria

AU - Mathiasen, Anders Bruun

AU - Elberg, Jens Jørgen

AU - Andersen, Peter Stemann

AU - Drzewiecki, Krzysztof Tadeusz

AU - Fischer-Nielsen, Anne

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AB - Because of an increasing focus on the use of adipose-derived stem cells (ASCs) in clinical trials, the culture conditions for these cells are being optimized. We compared the proliferation rates and chromosomal stability of ASCs that had been cultured in Dulbecco's modified Eagle's Medium (DMEM) supplemented with either pooled human platelet lysate (pHPL) or clinical-grade fetal bovine serum (FBS) (DMEM(pHPL) versus DMEM(FBS)).

UR - https://www.scopus.com/pages/publications/84881102185

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DO - 10.1016/j.jcyt.2013.01.217

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Pooled human platelet lysate versus fetal bovine serum-investigating the proliferation rate, chromosome stability and angiogenic potential of human adipose tissue-derived stem cells intended for clinical use

Abstract

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