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Pooled analysis of phase II trials evaluating weekly or conventional cisplatin as first-line therapy for advanced urothelial carcinoma

Benjamin L Maughan, Neeraj Agarwal, Syed A Hussain, Kenneth M Boucher, Hans Von Der Maase, Donald S Kaufman, Vito Lorusso, Malcolm J Moore, Matthew D Galsky, Guru Sonpavde

    6 Citations (Scopus)

    Abstract

    Weekly gemcitabine with GC every 3-4 weeks is considered conventional first-line chemotherapy for advanced urothelial carcinoma (UC). Weekly split-dose cisplatin with wGC might be less toxic and have similar activity, but has not been compared with GC. We pooled published phase II trials of GC and wGC to compare efficacy and safety.
    Original languageEnglish
    JournalClinical Genitourinary Cancer (Online)
    Volume11
    Issue number3
    Pages (from-to)316-20
    Number of pages5
    ISSN1938-0682
    DOIs
    Publication statusPublished - Sept 2013

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