Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Polypharmacy and medication deprescribing: A survey among multimorbid older adults in Denmark

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. Pharmacokinetic variability of beta-adrenergic blocking agents used in cardiology

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Inconsistencies in dosage practice in children with overweight or obesity: A retrospective cohort study

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Clinical trial allocation in multinational pharmaceutical companies - a qualitative study on influential factors

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Mechanical and vasomotor properties of piglet isolated middle cerebral artery

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Biased small-molecule ligands for selective inhibition of HIV-1 cell entry via CCR5

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Glucagon-like peptide-1 receptor regulation of basal dopamine transporter activity is species-dependent

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Glycemic control and use of glucose-lowering medications in hospital-admitted type 2 diabetes patients over 80 years

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. GIP and GLP-1 Receptor Antagonism During a Meal in Healthy Individuals

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

Polypharmacy is common among multimorbid adults and associated with increased morbidity and mortality. Excessive polypharmacy (ie, ≥10 medicine) is strongly associated with inappropriate medication use, but little is known about attitudes toward deprescribing in patients with excessive polypharmacy. We surveyed 100 Danish individuals aged 65 years and above with ≥10 prescribed medications, using the validated Patients' Attitudes Towards Deprescribing (PATD) instrument. Most participants (81, 81%) thought they took a large number of medications, and 79 (79%) believed that their medications were necessary. Even so, 85 (85%) reported that they would be willing to stop taking one or more of their regular medications if their doctor told them they could, and 11 (11%) felt that they took at least one regular medication that they no longer needed. When presented with visual presentation of various amounts of tablets and capsules, 62 (62%) of participants reported that they would be comfortable taking fewer medications than they did. Forty-two (42%) participants had experience with stopping a regular medication. Almost all participants (92%) wanted to receive follow-up by various means if a medication was discontinued. Forty-one (41%) participants were interested in a consultation at an outpatient clinic specializing in polypharmacy. Overall, the answers to the PATD questionnaire suggest that our cohort of Danish, multimorbid outpatients with extensive polypharmacy have a high confidence in their healthcare providers for medication-related decisions, even though some feel that they are taking more medications than they would like to and feel that some medications may be unnecessary. Our results underline the need for healthcare providers to offer medication reviews in patients with multimorbidity.

Original languageEnglish
JournalPharmacology Research & Perspectives
Volume6
Issue number6
Pages (from-to)e00431
ISSN2052-1707
DOIs
Publication statusPublished - Dec 2018

ID: 55567917