Polymorphisms of innate pattern recognition receptors, response to interferon-beta and development of neutralizing antibodies in multiple sclerosis patients

Christian Enevold; Annette B Oturai; Per Soelberg Sørensen; Lars P Ryder; Nils Koch-Henriksen; Klaus Bendtzen

doi:10.1177/1352458510373264

Polymorphisms of innate pattern recognition receptors, response to interferon-beta and development of neutralizing antibodies in multiple sclerosis patients

Christian Enevold, Annette B Oturai, Per Soelberg Sørensen, Lars P Ryder, Nils Koch-Henriksen, Klaus Bendtzen

32 Citations (Scopus)

Abstract

Interferon-beta therapy of patients with relapsing-remitting multiple sclerosis involves repeated 'immunizations' with exogenous protein solutions. Innate pattern recognition receptors play an important role in immune responses towards foreign substances and may thus be related to treatment outcome.

Original language	English
Journal	Multiple sclerosis
Volume	16
Issue number	8
Pages (from-to)	942-9
Number of pages	8
DOIs	https://doi.org/10.1177/1352458510373264
Publication status	Published - 1 Aug 2010

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Polymorphisms of innate pattern recognition receptors, response to interferon-beta and development of neutralizing antibodies in multiple sclerosis patients. / Enevold, Christian; Oturai, Annette B; Sørensen, Per Soelberg et al.
In: Multiple sclerosis, Vol. 16, No. 8, 01.08.2010, p. 942-9.

Research output: Contribution to journal › Journal article › Research › peer-review

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abstract = "Interferon-beta therapy of patients with relapsing-remitting multiple sclerosis involves repeated 'immunizations' with exogenous protein solutions. Innate pattern recognition receptors play an important role in immune responses towards foreign substances and may thus be related to treatment outcome.",

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AU - Enevold, Christian

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AU - Ryder, Lars P

AU - Koch-Henriksen, Nils

AU - Bendtzen, Klaus

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AB - Interferon-beta therapy of patients with relapsing-remitting multiple sclerosis involves repeated 'immunizations' with exogenous protein solutions. Innate pattern recognition receptors play an important role in immune responses towards foreign substances and may thus be related to treatment outcome.

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Polymorphisms of innate pattern recognition receptors, response to interferon-beta and development of neutralizing antibodies in multiple sclerosis patients

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