Platformsforsøg

Translated title of the contribution: Platform trials

Anders Perner*, Maj-Brit N Kjær, Hans-Christian Thorsen-Meyer, Benjamin S Kaas-Hansen, Marie W Munch, Marie O Collet, Camilla Rl Bruun, Aksel K. G. Jensen, Theis Lange, Trine Albertsen, Claus Duedal Pedersen, Lone M Poulsen, Ole Mathiesen, Anne C Brøchner, Thomas Strøm, Lars W Andersen, Steffen Christensen, Bodil S Rasmussen, Olav L Schjørring, Mathias MaagaardMorten Hylander Møller, Anders Granholm

*Corresponding author for this work

Abstract

Platform trials focus on the perpetual testing of many interventions in a disease or a setting. These trials have lasting organizational, administrative, data, analytic, and operational frameworks making them highly efficient. The use of adaptation often increases the probabilities of allocating participants to better interventions and obtaining conclusive results. The COVID-19 pandemic showed the potential of platform trials as a fast and valid way to improved treatments. This review gives an overview of key concepts and elements using the Intensive Care Platform Trial (INCEPT) as an example.

Translated title of the contributionPlatform trials
Original languageDanish
Article numberV04230237
JournalUgeskrift for Laeger
Volume185
Issue number41
ISSN0041-5782
Publication statusPublished - 9 Oct 2023

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