Plasma TIMP-1 levels and treatment outcome in patients treated with XELOX for metastatic colorectal cancer

C Frederiksen; C Qvortrup; I J Christensen; B Glimelius; A Berglund; B V Jensen; Svend Erik Nielsen; N Keldsen; H J Nielsen; Nils Aage Brünner; P Pfeiffer

doi:10.1093/annonc/mdq354

Plasma TIMP-1 levels and treatment outcome in patients treated with XELOX for metastatic colorectal cancer

C Frederiksen, C Qvortrup, I J Christensen, B Glimelius, A Berglund, B V Jensen, Svend Erik Nielsen, N Keldsen, H J Nielsen, Nils Aage Brünner, P Pfeiffer

20 Citations (Scopus)

Abstract

The aim was to evaluate the association between plasma tissue inhibitor of metalloproteinase-1 (TIMP-1) and serum carcinoembryonic antigen (CEA) levels and outcome in patients with metastatic colorectal cancer (mCRC) receiving XELOX (combination chemotherapy with capecitabine and oxaliplatin) as first-line treatment.

Original language	English
Journal	Annals of Oncology
Volume	22
Issue number	2
Pages (from-to)	369-75
Number of pages	7
ISSN	0923-7534
DOIs	https://doi.org/10.1093/annonc/mdq354
Publication status	Published - 2011

Keywords

Adult
Aged
Aged, 80 and over
Antineoplastic Combined Chemotherapy Protocols
Colorectal Neoplasms
Deoxycytidine
Female
Fluorouracil
Humans
Male
Middle Aged
Neoplasm Metastasis
Survival Analysis
Tissue Inhibitor of Metalloproteinase-1
Treatment Outcome

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10.1093/annonc/mdq354

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title = "Plasma TIMP-1 levels and treatment outcome in patients treated with XELOX for metastatic colorectal cancer",

abstract = "The aim was to evaluate the association between plasma tissue inhibitor of metalloproteinase-1 (TIMP-1) and serum carcinoembryonic antigen (CEA) levels and outcome in patients with metastatic colorectal cancer (mCRC) receiving XELOX (combination chemotherapy with capecitabine and oxaliplatin) as first-line treatment.",

keywords = "Adult, Aged, Aged, 80 and over, Antineoplastic Combined Chemotherapy Protocols, Colorectal Neoplasms, Deoxycytidine, Female, Fluorouracil, Humans, Male, Middle Aged, Neoplasm Metastasis, Survival Analysis, Tissue Inhibitor of Metalloproteinase-1, Treatment Outcome",

author = "C Frederiksen and C Qvortrup and Christensen, \{I J\} and B Glimelius and A Berglund and Jensen, \{B V\} and Nielsen, \{Svend Erik\} and N Keldsen and Nielsen, \{H J\} and Br{\"u}nner, \{Nils Aage\} and P Pfeiffer",

year = "2011",

doi = "10.1093/annonc/mdq354",

language = "English",

volume = "22",

pages = "369--75",

journal = "Annals of Oncology",

issn = "0923-7534",

publisher = "Elsevier Limited",

number = "2",

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TY - JOUR

T1 - Plasma TIMP-1 levels and treatment outcome in patients treated with XELOX for metastatic colorectal cancer

AU - Frederiksen, C

AU - Qvortrup, C

AU - Christensen, I J

AU - Glimelius, B

AU - Berglund, A

AU - Jensen, B V

AU - Nielsen, Svend Erik

AU - Keldsen, N

AU - Nielsen, H J

AU - Brünner, Nils Aage

AU - Pfeiffer, P

PY - 2011

Y1 - 2011

N2 - The aim was to evaluate the association between plasma tissue inhibitor of metalloproteinase-1 (TIMP-1) and serum carcinoembryonic antigen (CEA) levels and outcome in patients with metastatic colorectal cancer (mCRC) receiving XELOX (combination chemotherapy with capecitabine and oxaliplatin) as first-line treatment.

AB - The aim was to evaluate the association between plasma tissue inhibitor of metalloproteinase-1 (TIMP-1) and serum carcinoembryonic antigen (CEA) levels and outcome in patients with metastatic colorectal cancer (mCRC) receiving XELOX (combination chemotherapy with capecitabine and oxaliplatin) as first-line treatment.

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Antineoplastic Combined Chemotherapy Protocols

KW - Colorectal Neoplasms

KW - Deoxycytidine

KW - Female

KW - Fluorouracil

KW - Humans

KW - Male

KW - Middle Aged

KW - Neoplasm Metastasis

KW - Survival Analysis

KW - Tissue Inhibitor of Metalloproteinase-1

KW - Treatment Outcome

UR - https://www.scopus.com/pages/publications/79251571485

U2 - 10.1093/annonc/mdq354

DO - 10.1093/annonc/mdq354

M3 - Journal article

C2 - 20643864

SN - 0923-7534

VL - 22

SP - 369

EP - 375

JO - Annals of Oncology

JF - Annals of Oncology

IS - 2

ER -

Plasma TIMP-1 levels and treatment outcome in patients treated with XELOX for metastatic colorectal cancer

Abstract

Keywords

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