Pitfalls in diagnostic gastrin measurements

Jens F Rehfeld, Linda Bardram, Linda Hilsted, Pierre Poitras, Jens P Goetze

35 Citations (Scopus)

Abstract

Gastrin measurements are performed primarily for the diagnosis of gastrin-producing tumors, gastrinomas, which cause the Zollinger-Ellison syndrome (ZES). Gastrin circulates as several bioactive peptides, however, and the peptide pattern in gastrinoma patients often deviates from normal. Therefore, it is necessary to measure all forms of gastrin.
Original languageEnglish
JournalClinical Chemistry (Washington, DC)
Volume58
Issue number5
Pages (from-to)831-6
Number of pages6
ISSN0009-9147
DOIs
Publication statusPublished - 2012

Keywords

  • Amino Acid Sequence
  • Antibody Specificity
  • Gastrinoma
  • Gastrins
  • Humans
  • Immunoassay
  • Molecular Sequence Data
  • Reagent Kits, Diagnostic
  • Sensitivity and Specificity
  • Tumor Markers, Biological
  • Zollinger-Ellison Syndrome

Fingerprint

Dive into the research topics of 'Pitfalls in diagnostic gastrin measurements'. Together they form a unique fingerprint.

Cite this