Phenotypes of individuals affected by airborne chemicals in the general population.

Nikolaj Drimer Berg; Allan Linneberg; Asger Dirksen; Jesper Elberling

doi:10.1007/s00420-008-0352-y

Phenotypes of individuals affected by airborne chemicals in the general population.

Nikolaj Drimer Berg, Allan Linneberg, Asger Dirksen, Jesper Elberling

28 Citations (Scopus)

Abstract

OBJECTIVE: To characterise the chemical exposures and symptoms affecting individuals with subsequent adjustments of social life or occupational conditions, and further characterise these severely affected individuals.

METHODS: All individuals (n = 1,134) who reported symptoms from airborne chemical exposures in a population-based questionnaire study of 6,000 individuals were included and dichotomised according to severity. Logistic regression models were used to characterise the group of severely affected individuals.

RESULTS: Severely affected individuals reported more symptoms and exposures related to symptoms than less severely affected individuals, and the number of symptoms was more predictive for severity than the number of exposures. Most predictive for the severity of reported symptoms were CNS-symptoms other than headache (OR = 3.2, P <0.001) and exposure to freshly printed papers or magazines (OR = 2.0, P = 0.001).

CONCLUSION: CNS-symptoms except from headache were a main characteristic of individuals severely affected by common chemical exposures in a general population-based sample

Original language	Danish
Journal	International Archives of Occupational and Environmental Health
Volume	82
Issue number	4
Pages (from-to)	509-517
Number of pages	9
ISSN	0340-0131
DOIs	https://doi.org/10.1007/s00420-008-0352-y
Publication status	Published - 2009

Keywords

Adolescent
Adult
Aged
Air Pollutants
Air Pollution
Cross-Sectional Studies
Denmark
Female
Health Status
Humans
Inhalation Exposure
Logistic Models
Male
Middle Aged
Multiple Chemical Sensitivity
Phenotype
Quality of Life
Questionnaires
Young Adult

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10.1007/s00420-008-0352-y

Cite this

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title = "Phenotypes of individuals affected by airborne chemicals in the general population.",

abstract = "OBJECTIVE: To characterise the chemical exposures and symptoms affecting individuals with subsequent adjustments of social life or occupational conditions, and further characterise these severely affected individuals. METHODS: All individuals (n = 1,134) who reported symptoms from airborne chemical exposures in a population-based questionnaire study of 6,000 individuals were included and dichotomised according to severity. Logistic regression models were used to characterise the group of severely affected individuals. RESULTS: Severely affected individuals reported more symptoms and exposures related to symptoms than less severely affected individuals, and the number of symptoms was more predictive for severity than the number of exposures. Most predictive for the severity of reported symptoms were CNS-symptoms other than headache (OR = 3.2, P <0.001) and exposure to freshly printed papers or magazines (OR = 2.0, P = 0.001). CONCLUSION: CNS-symptoms except from headache were a main characteristic of individuals severely affected by common chemical exposures in a general population-based sample",

keywords = "Adolescent, Adult, Aged, Air Pollutants, Air Pollution, Cross-Sectional Studies, Denmark, Female, Health Status, Humans, Inhalation Exposure, Logistic Models, Male, Middle Aged, Multiple Chemical Sensitivity, Phenotype, Quality of Life, Questionnaires, Young Adult",

author = "Berg, \{Nikolaj Drimer\} and Allan Linneberg and Asger Dirksen and Jesper Elberling",

year = "2009",

doi = "10.1007/s00420-008-0352-y",

language = "Dansk",

volume = "82",

pages = "509--517",

journal = "International Archives of Occupational and Environmental Health",

issn = "0340-0131",

publisher = "Springer Science and Business Media Deutschland GmbH",

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TY - JOUR

T1 - Phenotypes of individuals affected by airborne chemicals in the general population.

AU - Berg, Nikolaj Drimer

AU - Linneberg, Allan

AU - Dirksen, Asger

AU - Elberling, Jesper

PY - 2009

Y1 - 2009

N2 - OBJECTIVE: To characterise the chemical exposures and symptoms affecting individuals with subsequent adjustments of social life or occupational conditions, and further characterise these severely affected individuals. METHODS: All individuals (n = 1,134) who reported symptoms from airborne chemical exposures in a population-based questionnaire study of 6,000 individuals were included and dichotomised according to severity. Logistic regression models were used to characterise the group of severely affected individuals. RESULTS: Severely affected individuals reported more symptoms and exposures related to symptoms than less severely affected individuals, and the number of symptoms was more predictive for severity than the number of exposures. Most predictive for the severity of reported symptoms were CNS-symptoms other than headache (OR = 3.2, P <0.001) and exposure to freshly printed papers or magazines (OR = 2.0, P = 0.001). CONCLUSION: CNS-symptoms except from headache were a main characteristic of individuals severely affected by common chemical exposures in a general population-based sample

AB - OBJECTIVE: To characterise the chemical exposures and symptoms affecting individuals with subsequent adjustments of social life or occupational conditions, and further characterise these severely affected individuals. METHODS: All individuals (n = 1,134) who reported symptoms from airborne chemical exposures in a population-based questionnaire study of 6,000 individuals were included and dichotomised according to severity. Logistic regression models were used to characterise the group of severely affected individuals. RESULTS: Severely affected individuals reported more symptoms and exposures related to symptoms than less severely affected individuals, and the number of symptoms was more predictive for severity than the number of exposures. Most predictive for the severity of reported symptoms were CNS-symptoms other than headache (OR = 3.2, P <0.001) and exposure to freshly printed papers or magazines (OR = 2.0, P = 0.001). CONCLUSION: CNS-symptoms except from headache were a main characteristic of individuals severely affected by common chemical exposures in a general population-based sample

KW - Adolescent

KW - Adult

KW - Aged

KW - Air Pollutants

KW - Air Pollution

KW - Cross-Sectional Studies

KW - Denmark

KW - Female

KW - Health Status

KW - Humans

KW - Inhalation Exposure

KW - Logistic Models

KW - Male

KW - Middle Aged

KW - Multiple Chemical Sensitivity

KW - Phenotype

KW - Quality of Life

KW - Questionnaires

KW - Young Adult

UR - https://www.scopus.com/pages/publications/61349188953

U2 - 10.1007/s00420-008-0352-y

DO - 10.1007/s00420-008-0352-y

M3 - Tidsskriftartikel

C2 - 18751996

SN - 0340-0131

VL - 82

SP - 509

EP - 517

JO - International Archives of Occupational and Environmental Health

JF - International Archives of Occupational and Environmental Health

IS - 4

ER -

Phenotypes of individuals affected by airborne chemicals in the general population.

Abstract

Keywords

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