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Pharmacological attenuation of myocardial reperfusion injury in a closed-chest porcine model: a systematic review

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  3. Mesenteric Lymphadenitis and Terminal Ileitis is Associated With Yersinia Infection: A Meta-analysis

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  4. Inguinal hernia repair among men: development and validation of a preoperative risk score for persistent postoperative pain

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Myocardial ischemia-reperfusion injury is a clinical challenge in interventional cardiology, and at the moment, no pharmacological agent is universally accepted in the prevention. In order to prevent inappropriate clinical trials, a potential pharmacological agent should be proved reproducibly effective in clinically relevant experimental studies before initiation of human studies. The closed-chest porcine model is a promising experimental model of ischemia-reperfusion injury. The purpose of this systematic review was to describe the pharmacological treatments evaluated in the closed-chest porcine model and discuss different aspects of the model for future use. The systematic review was performed according to the PRISMA guidelines.

Original languageEnglish
JournalJournal of Cardiovascular Translational Research
Volume7
Issue number6
Pages (from-to)570-80
Number of pages11
ISSN1937-5387
DOIs
Publication statusPublished - Aug 2014

ID: 44542857