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The Capital Region of Denmark - a part of Copenhagen University Hospital
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PET imaging in patients with brain metastasis-report of the RANO/PET group

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  1. Sex-specific gene and pathway modeling of inherited glioma risk

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  2. Genome-wide association analysis identifies a meningioma risk locus at 11p15.5

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  3. VEGF-C Sustains VEGFR2 Activation under Bevacizumab Therapy and Promotes Glioblastoma Maintenance

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  1. PET imaging of meningioma with 18F-FLT: a predictor of tumour progression

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  2. Effect of blood glucose and body weight on image quality in brain [18F]FDG PET imaging

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  3. Mania triggered by levodopa treatment in a patient with frontotemporal dementia caused by A C9orf72 repeat expansion: A case report

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  4. Pharmacokinetic analysis of [68Ga]Ga-DOTA-TOC PET in meningiomas for assessment of in vivo somatostatin receptor subtype 2

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  5. Validation of diffuse correlation spectroscopy against 15O-water PET for regional cerebral blood flow measurement in neonatal piglets

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  • Norbert Galldiks
  • Karl-Josef Langen
  • Nathalie L Albert
  • Marc Chamberlain
  • Riccardo Soffietti
  • Michelle M Kim
  • Ian Law
  • Emilie Le Rhun
  • Susan Chang
  • Julian Schwarting
  • Stephanie E Combs
  • Matthias Preusser
  • Peter Forsyth
  • Whitney Pope
  • Michael Weller
  • Jörg C Tonn
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Brain metastases (BM) from extracranial cancer are associated with significant morbidity and mortality. Effective local treatment options are stereotactic radiotherapy, including radiosurgery or fractionated external beam radiotherapy, and surgical resection. The use of systemic treatment for intracranial disease control also is improving. BM diagnosis, treatment planning, and follow-up is most often based on contrast-enhanced magnetic resonance imaging (MRI). However, anatomic imaging modalities including standard MRI have limitations in accurately characterizing posttherapeutic reactive changes and treatment response. Molecular imaging techniques such as positron emission tomography (PET) characterize specific metabolic and cellular features of metastases, potentially providing clinically relevant information supplementing anatomic MRI. Here, the Response Assessment in Neuro-Oncology working group provides recommendations for the use of PET imaging in the clinical management of patients with BM based on evidence from studies validated by histology and/or clinical outcome.

Original languageEnglish
JournalNeuro-Oncology
Volume21
Issue number5
Pages (from-to)585-595
Number of pages11
ISSN1522-8517
DOIs
Publication statusPublished - 6 May 2019

ID: 59320346