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The Capital Region of Denmark - a part of Copenhagen University Hospital
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PET imaging in patients with brain metastasis-report of the RANO/PET group

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  1. Surgical resection of glioblastomas induces pleiotrophin-mediated self-renewal of glioblastoma stem cells in recurrent tumors

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Diagnostic Accuracy and Clinical Impact of [ 18F]FET PET in Childhood CNS tumors

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  3. Establishing anchor-based minimally important differences for the EORTC QLQ-C30 in glioma patients

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  4. Partitioned glioma heritability shows subtype-specific enrichment in immune cells

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Contribution of PET imaging to radiotherapy planning and monitoring in glioma patients - a report of the PET/RANO group

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  1. Proposal of a new grading system for meningioma resection: the Copenhagen Protocol

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Diagnostic Accuracy and Clinical Impact of [ 18F]FET PET in Childhood CNS tumors

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Deep-learning-based attenuation correction in dynamic [15O]H2O studies using PET/MRI in healthy volunteers

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. PET Imaging in Neurodegeneration and Neuro-oncology: Variants and Pitfalls

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  5. Finding our way through the labyrinth of dementia biomarkers

    Research output: Contribution to journalEditorialResearchpeer-review

  • Norbert Galldiks
  • Karl-Josef Langen
  • Nathalie L Albert
  • Marc Chamberlain
  • Riccardo Soffietti
  • Michelle M Kim
  • Ian Law
  • Emilie Le Rhun
  • Susan Chang
  • Julian Schwarting
  • Stephanie E Combs
  • Matthias Preusser
  • Peter Forsyth
  • Whitney Pope
  • Michael Weller
  • Jörg C Tonn
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Brain metastases (BM) from extracranial cancer are associated with significant morbidity and mortality. Effective local treatment options are stereotactic radiotherapy, including radiosurgery or fractionated external beam radiotherapy, and surgical resection. The use of systemic treatment for intracranial disease control also is improving. BM diagnosis, treatment planning, and follow-up is most often based on contrast-enhanced magnetic resonance imaging (MRI). However, anatomic imaging modalities including standard MRI have limitations in accurately characterizing posttherapeutic reactive changes and treatment response. Molecular imaging techniques such as positron emission tomography (PET) characterize specific metabolic and cellular features of metastases, potentially providing clinically relevant information supplementing anatomic MRI. Here, the Response Assessment in Neuro-Oncology working group provides recommendations for the use of PET imaging in the clinical management of patients with BM based on evidence from studies validated by histology and/or clinical outcome.

Original languageEnglish
JournalNeuro-Oncology
Volume21
Issue number5
Pages (from-to)585-595
Number of pages11
ISSN1522-8517
DOIs
Publication statusPublished - 6 May 2019

ID: 59320346