Persisterende pulmonal hypertension hos nyfødte

Translated title of the contribution: [Persistent pulmonary hypertension in newborn infants]

C M Pedersen, T G Hansen, S W Henneberg

Abstract

On the basis of a review of the literature, a survey is presented concerning persistent pulmonary hypertension of the newborn. In this article the authors focus on the pathophysiology, diagnostic criteria and treatment, including mechanical ventilation, pharmacological vasodilation and extracorporal membrane oxygenation. Particular emphasis is placed on the treatment of the condition with inhaled nitric oxide. Nitric oxide is a selective pulmonary vasodilator and able to improve ventilation/ perfusion mismatching in cases where there is an affection of the pulmonary parenchyma. Data from randomized trials with close long-term follow-up is necessary before routine nitrogen oxide treatment can be recommended.
Translated title of the contribution[Persistent pulmonary hypertension in newborn infants]
Original languageDanish
JournalUgeskrift for Laeger
Volume159
Issue number28
Pages (from-to)4377-82
Number of pages6
ISSN0041-5782
Publication statusPublished - 7 Jul 1997

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