Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Persistent organic pollutants, skull size and bone density of polar bears (Ursus maritimus) from East Greenland 1892-2015 and Svalbard 1964-2004

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Road and railway noise and risk for breast cancer: A nationwide study covering Denmark

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. The influence of prenatal exposure to phthalates on subsequent male growth and body composition in adolescence

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Use of stored serum in the study of time trends and geographical differences in exposure of pregnant women to phthalates

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Corticosteroid Resistance in Smokers-A Substudy Analysis of the CORTICO-COP Randomised Controlled Trial

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Adolescents with functional somatic syndromes: Symptom profiles, illness perception, illness worry and attachment orientation

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. ABO blood types and sepsis mortality

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Choice of dialysis modality: patients' experiences and quality of decision after shared decision-making

    Research output: Contribution to journalJournal articleResearchpeer-review

  • Tobias Daugaard-Petersen
  • Rikke Langebæk
  • Frank F Rigét
  • Robert J Letcher
  • Lars Hyldstrup
  • Jens-Erik Bech Jensen
  • Thea Bechshoft
  • Øystein Wiig
  • Bjørn Munro Jenssen
  • Cino Pertoldi
  • Eline D Lorenzen
  • Rune Dietz
  • Christian Sonne
View graph of relations

We investigated skull size (condylobasal length; CBL) and bone mineral density (BMD) in polar bears (Ursus maritimus) from East Greenland (n = 307) and Svalbard (n = 173) sampled during the period 1892-2015 in East Greenland and 1964-2004 at Svalbard. Adult males from East Greenland showed a continuous decrease in BMD from 1892 to 2015 (linear regression: p < 0.01) indicating that adult male skulls collected in the early pre-pollution period had the highest BMD. A similar decrease in BMD over time was not found for the East Greenland adult females. However, there was a non-significant trend that the skull size of adult East Greenland females was negatively correlated with collection year 1892-2015 (linear regression: p = 0.06). No temporal change was found for BMD or skull size in Svalbard polar bears (ANOVA: all p > 0.05) nor was there any significant difference in BMD between Svalbard and East Greenland subpopulations. Skull size was larger in polar bears from Svalbard than from East Greenland (two-way ANOVA: p = 0.003). T-scores reflecting risk of osteoporosis showed that adult males from both East Greenland and Svalbard are at risk of developing osteopenia. Finally, when correcting for age and sex, BMD in East Greenland polar bears increased with increasing concentrations of persistent organic pollutants (POPs) i.e. ΣPCB (polychlorinated biphenyls), ΣHCH (hexachlorohexane), HCB (hexachlorobenzene) and ΣPBDE (polybrominated diphenyl ethers) while skull size increased with ΣHCH concentrations all in the period 1999-2014 (multiple linear regression: all p < 0.05, n = 175). The results suggest that environmental changes over time, including exposure to POPs, may affect bone density and size of polar bears.

Original languageEnglish
JournalEnvironmental Research
Volume162
Pages (from-to)74-80
Number of pages7
ISSN0013-9351
DOIs
Publication statusPublished - Apr 2018

    Research areas

  • Journal Article

ID: 52363641