Permeability and ultrastructure of human bladder epithelium

J Eldrup; J Thorup; S L Nielsen; T Hald; B Hainau

doi:10.1111/j.1464-410x.1983.tb03354.x

Permeability and ultrastructure of human bladder epithelium

J Eldrup, J Thorup, S L Nielsen, T Hald, B Hainau

81 Citations (Scopus)

Abstract

Leakage of tight junctions as observed with electron microscopy and demonstration of solute transport across bladder epithelium was investigated in 13 patients with different bladder diseases: urinary retention and infection, bladder tumours and interstitial cystitis. The latter group showed consistent leakage of solutes through the urothelium. Electron microscopy revealed leaky tight junctions. This finding might be helpful in establishing the histological criteria and explain the pathogenesis of interstitial cystitis.

Original language	English
Journal	British Journal of Urology
Volume	55
Issue number	5
Pages (from-to)	488-92
Number of pages	5
ISSN	0007-1331
DOIs	https://doi.org/10.1111/j.1464-410x.1983.tb03354.x
Publication status	Published - Oct 1983
Externally published	Yes

Keywords

Adult
Albumins/metabolism
Cell Membrane Permeability
Epithelium/metabolism
Female
Humans
Intercellular Junctions/ultrastructure
Male
Microscopy, Electron
Middle Aged
Sodium/metabolism
Urea/metabolism
Urinary Bladder/metabolism
Urologic Diseases/metabolism

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10.1111/j.1464-410x.1983.tb03354.x

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title = "Permeability and ultrastructure of human bladder epithelium",

abstract = "Leakage of tight junctions as observed with electron microscopy and demonstration of solute transport across bladder epithelium was investigated in 13 patients with different bladder diseases: urinary retention and infection, bladder tumours and interstitial cystitis. The latter group showed consistent leakage of solutes through the urothelium. Electron microscopy revealed leaky tight junctions. This finding might be helpful in establishing the histological criteria and explain the pathogenesis of interstitial cystitis.",

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author = "J Eldrup and J Thorup and Nielsen, \{S L\} and T Hald and B Hainau",

year = "1983",

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doi = "10.1111/j.1464-410x.1983.tb03354.x",

language = "English",

volume = "55",

pages = "488--92",

journal = "British Journal of Urology",

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TY - JOUR

T1 - Permeability and ultrastructure of human bladder epithelium

AU - Eldrup, J

AU - Thorup, J

AU - Nielsen, S L

AU - Hald, T

AU - Hainau, B

PY - 1983/10

Y1 - 1983/10

N2 - Leakage of tight junctions as observed with electron microscopy and demonstration of solute transport across bladder epithelium was investigated in 13 patients with different bladder diseases: urinary retention and infection, bladder tumours and interstitial cystitis. The latter group showed consistent leakage of solutes through the urothelium. Electron microscopy revealed leaky tight junctions. This finding might be helpful in establishing the histological criteria and explain the pathogenesis of interstitial cystitis.

AB - Leakage of tight junctions as observed with electron microscopy and demonstration of solute transport across bladder epithelium was investigated in 13 patients with different bladder diseases: urinary retention and infection, bladder tumours and interstitial cystitis. The latter group showed consistent leakage of solutes through the urothelium. Electron microscopy revealed leaky tight junctions. This finding might be helpful in establishing the histological criteria and explain the pathogenesis of interstitial cystitis.

KW - Adult

KW - Albumins/metabolism

KW - Cell Membrane Permeability

KW - Epithelium/metabolism

KW - Female

KW - Humans

KW - Intercellular Junctions/ultrastructure

KW - Male

KW - Microscopy, Electron

KW - Middle Aged

KW - Sodium/metabolism

KW - Urea/metabolism

KW - Urinary Bladder/metabolism

KW - Urologic Diseases/metabolism

UR - https://www.scopus.com/pages/publications/0020612878

U2 - 10.1111/j.1464-410x.1983.tb03354.x

DO - 10.1111/j.1464-410x.1983.tb03354.x

M3 - Journal article

C2 - 6626894

SN - 0007-1331

VL - 55

SP - 488

EP - 492

JO - British Journal of Urology

JF - British Journal of Urology

IS - 5

ER -

Permeability and ultrastructure of human bladder epithelium

Abstract

Keywords

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