Peripheral nerve blocks for closed reduction of distal radius fractures-A protocol for a systematic review

Sanja Pisljagic*, Jens L Temberg, Mathias T Steensbaek, Sina Yousef, Mathias Maagaard, Lana Chafranska, Kai H W Lange, Christian Rothe, Lars H Lundstrøm, Anders K Nørskov

*Corresponding author for this work

Abstract

BACKGROUND: Current methods of anaesthesia used for closed reduction of distal radial fractures may be insufficient for pain relief and muscle relaxation, potentially compromising reduction quality and patient satisfaction. Peripheral nerve blocks have already been implemented for surgery of wrist fractures and may provide optimal conditions for closed reduction due to complete motor and sensory blockade of the involved nerves. However, existing literature on peripheral nerve blocks for closed reduction is sparse, and no updated systematic review or meta-analysis exists.

AIMS: This protocol is developed according to the PRISMA-P statement. The systematic review and meta-analysis aim to consolidate the literature regarding the effect and harm of peripheral nerve blocks compared with other anaesthesia modalities for closed reduction of distal radius fractures in adults.

METHODS: The two primary outcomes are the proportion of participants needing surgery after closed reduction and pain during closed reduction. We will only include randomised clinical trials. Two review authors will each independently screen literature, extract data, and assess risk of bias with Risk of Bias 2 Tool. Meta-analysis will be carried out with Rstudio. We will also perform a Trial Sequential Analysis. The certainty of evidence will be judged using GRADE guidelines.

DISCUSSION: We will use up-to-date methodology when conducting the systematic review outlined in this protocol. The results may guide clinicians in their decision-making regarding the use of anaesthesia for closed reduction of distal radius fractures in adults.

Original languageEnglish
JournalActa Anaesthesiologica Scandinavica
Volume68
Issue number3
Pages (from-to)423-429
Number of pages7
ISSN0001-5172
DOIs
Publication statusPublished - Mar 2024

Keywords

  • Adult
  • Anesthesia, Conduction
  • Humans
  • Meta-Analysis as Topic
  • Pain
  • Peripheral Nerves
  • Systematic Reviews as Topic
  • Wrist Fractures

Fingerprint

Dive into the research topics of 'Peripheral nerve blocks for closed reduction of distal radius fractures-A protocol for a systematic review'. Together they form a unique fingerprint.

Cite this