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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Peripheral artery disease (PAD) screening in the asymptomatic population: why, how, and who?

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  1. Coronary Microvascular Dysfunction: A Practical Approach to Diagnosis and Management

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  2. Genetics of Lipoprotein(a): Cardiovascular Disease and Future Therapy

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  3. Antisense Oligonucleotides Targeting Lipoprotein(a)

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  4. Peripheral Arterial Disease in Women: an Overview of Risk Factor Profile, Clinical Features, and Outcomes

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  5. Non-invasive imaging for subclinical coronary atherosclerosis in patients with peripheral artery disease

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  1. Carotid plaque thickness is increased in chronic kidney disease and associated with carotid and coronary calcification

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  2. The Short-term Predictive Value of Vessel Wall Stiffness on Abdominal Aortic Aneurysm Growth

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  3. Three-dimensional ultrasound improves identification of patients with abdominal aortic aneurysms reaching the threshold for repair

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Measurement of ankle-brachial index (ABI) was developed to assess peripheral artery disease (PAD) in patients with symptoms of peripheral ischemia being present at rest or only functionally dependent (intermittent claudication). Reduced ABI is caused by arterial obstruction between the aortic arch and feet (lower limb), which in the Western world is caused by atherosclerosis if not previous trauma. Whereas severity of intermittent claudication is only poorly related to ABI, cardiovascular outcomes are as follows: the lower the ABI the higher the incidence of cardiovascular events and death. Measuring ABI identifies asymptomatic persons at increased risk of cardiovascular morbidity and mortality: an ABI 25% in people between 80 and 90 years of age. The majority of persons with reduced ABI are asymptomatic and therefore unaware of the increased risk they are living with, thus, screening by measuring ABI offers the opportunity for identifying persons at high risk. Unfortunately, most primary care physicians are not performing ABI in their office. Reimbursement issues along with inadequate knowledge of ABI are barriers for adoption and must be addressed.
Original languageEnglish
JournalCurrent Atherosclerosis Reports
Volume13
Issue number5
Pages (from-to)390-5
Number of pages6
ISSN1523-3804
DOIs
Publication statusPublished - 2011

ID: 33198248