Peripheral and central mechanisms in tension-type headache: an update

Rigmor Højland Jensen

doi:10.1046/j.1468-2982.2003.00574.x

Peripheral and central mechanisms in tension-type headache: an update

Abstract

Despite the tremendous socioeconomic impact of tension-type headache surprisingly little is known about the underlying pathophysiology and treatment. Existing evidence and theories about the relation between central and peripheral mechanisms are discussed. Central sensitization is probably the most important key to understand this widespread disorder. An effective prevention or reversal of this central sensitization will probably be of major importance in future treatment strategies.

Original language	English
Journal	Cephalalgia : an international journal of headache
Volume	23 Suppl 1
Pages (from-to)	49-52
Number of pages	4
ISSN	0333-1024
DOIs	https://doi.org/10.1046/j.1468-2982.2003.00574.x
Publication status	Published - 2003
Externally published	Yes

Keywords

Animals
Central Nervous System/physiopathology
Humans
Migraine Disorders/complications
Nitric Oxide/metabolism
Nociceptors/physiology
Peripheral Nervous System/physiopathology
Tension-Type Headache/complications

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10.1046/j.1468-2982.2003.00574.x

Cite this

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title = "Peripheral and central mechanisms in tension-type headache: an update",

abstract = "Despite the tremendous socioeconomic impact of tension-type headache surprisingly little is known about the underlying pathophysiology and treatment. Existing evidence and theories about the relation between central and peripheral mechanisms are discussed. Central sensitization is probably the most important key to understand this widespread disorder. An effective prevention or reversal of this central sensitization will probably be of major importance in future treatment strategies.",

keywords = "Animals, Central Nervous System/physiopathology, Humans, Migraine Disorders/complications, Nitric Oxide/metabolism, Nociceptors/physiology, Peripheral Nervous System/physiopathology, Tension-Type Headache/complications",

author = "Jensen, {Rigmor H{\o}jland}",

year = "2003",

doi = "10.1046/j.1468-2982.2003.00574.x",

language = "English",

volume = "23 Suppl 1",

pages = "49--52",

journal = "Cephalalgia : an international journal of headache",

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TY - JOUR

T1 - Peripheral and central mechanisms in tension-type headache

T2 - an update

AU - Jensen, Rigmor Højland

PY - 2003

Y1 - 2003

N2 - Despite the tremendous socioeconomic impact of tension-type headache surprisingly little is known about the underlying pathophysiology and treatment. Existing evidence and theories about the relation between central and peripheral mechanisms are discussed. Central sensitization is probably the most important key to understand this widespread disorder. An effective prevention or reversal of this central sensitization will probably be of major importance in future treatment strategies.

AB - Despite the tremendous socioeconomic impact of tension-type headache surprisingly little is known about the underlying pathophysiology and treatment. Existing evidence and theories about the relation between central and peripheral mechanisms are discussed. Central sensitization is probably the most important key to understand this widespread disorder. An effective prevention or reversal of this central sensitization will probably be of major importance in future treatment strategies.

KW - Animals

KW - Central Nervous System/physiopathology

KW - Humans

KW - Migraine Disorders/complications

KW - Nitric Oxide/metabolism

KW - Nociceptors/physiology

KW - Peripheral Nervous System/physiopathology

KW - Tension-Type Headache/complications

U2 - 10.1046/j.1468-2982.2003.00574.x

DO - 10.1046/j.1468-2982.2003.00574.x

M3 - Review

C2 - 12699459

SN - 0333-1024

VL - 23 Suppl 1

SP - 49

EP - 52

JO - Cephalalgia : an international journal of headache

JF - Cephalalgia : an international journal of headache

ER -

Peripheral and central mechanisms in tension-type headache: an update

Abstract

Keywords

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