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Percutaneous pulmonary valve replacement after different duration of free pulmonary regurgitation in a porcine model: Effects on the right ventricle

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@article{3b8e57f3b4a84b4ba36a076a7563f5e0,
title = "Percutaneous pulmonary valve replacement after different duration of free pulmonary regurgitation in a porcine model: Effects on the right ventricle",
abstract = "BACKGROUND: Free pulmonary regurgitation (PR) after surgical correction of Tetralogy of Fallot (ToF) with transannular patching can lead to irreversible right ventricular (RV) failure. However, the optimal timing of valve replacement is still debated. METHODS AND RESULTS: Thirty six pigs were included in the study. Twenty one pigs had a bare metal stent placed in the pulmonary annulus inducing free PR and 9 animals served as control. Six animals died prematurely due to procedural complications. The 21 animals were divided into 3 groups with differential duration of PR (1, 2, 3months, respectively) after which PPVR was performed. After 1month with competent valve the animals were euthanized. Cardiac magnetic resonance (CMR) and right heart catheterization were performed serially. Free PR led to severe dilation of the RV in all three groups compared to matched controls (p",
author = "Mads Ersboell and Niels Vejlstrup and Nilsson, {Jens Christian} and Jesper Kjaergaard and Wendy Norman and Theis Lange and Andrew Taylor and Philipp Bonhoeffer and Lars Sondergaard",
note = "Copyright {\textcopyright} 2012 Elsevier Ireland Ltd. All rights reserved.",
year = "2013",
doi = "10.1016/j.ijcard.2012.08.012",
language = "English",
volume = "167",
pages = "2944--51",
journal = "International Journal of Cardiology",
issn = "0167-5273",
publisher = "Elsevier Ireland Ltd",
number = "6",

}

RIS

TY - JOUR

T1 - Percutaneous pulmonary valve replacement after different duration of free pulmonary regurgitation in a porcine model

T2 - Effects on the right ventricle

AU - Ersboell, Mads

AU - Vejlstrup, Niels

AU - Nilsson, Jens Christian

AU - Kjaergaard, Jesper

AU - Norman, Wendy

AU - Lange, Theis

AU - Taylor, Andrew

AU - Bonhoeffer, Philipp

AU - Sondergaard, Lars

N1 - Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

PY - 2013

Y1 - 2013

N2 - BACKGROUND: Free pulmonary regurgitation (PR) after surgical correction of Tetralogy of Fallot (ToF) with transannular patching can lead to irreversible right ventricular (RV) failure. However, the optimal timing of valve replacement is still debated. METHODS AND RESULTS: Thirty six pigs were included in the study. Twenty one pigs had a bare metal stent placed in the pulmonary annulus inducing free PR and 9 animals served as control. Six animals died prematurely due to procedural complications. The 21 animals were divided into 3 groups with differential duration of PR (1, 2, 3months, respectively) after which PPVR was performed. After 1month with competent valve the animals were euthanized. Cardiac magnetic resonance (CMR) and right heart catheterization were performed serially. Free PR led to severe dilation of the RV in all three groups compared to matched controls (p

AB - BACKGROUND: Free pulmonary regurgitation (PR) after surgical correction of Tetralogy of Fallot (ToF) with transannular patching can lead to irreversible right ventricular (RV) failure. However, the optimal timing of valve replacement is still debated. METHODS AND RESULTS: Thirty six pigs were included in the study. Twenty one pigs had a bare metal stent placed in the pulmonary annulus inducing free PR and 9 animals served as control. Six animals died prematurely due to procedural complications. The 21 animals were divided into 3 groups with differential duration of PR (1, 2, 3months, respectively) after which PPVR was performed. After 1month with competent valve the animals were euthanized. Cardiac magnetic resonance (CMR) and right heart catheterization were performed serially. Free PR led to severe dilation of the RV in all three groups compared to matched controls (p

U2 - 10.1016/j.ijcard.2012.08.012

DO - 10.1016/j.ijcard.2012.08.012

M3 - Journal article

C2 - 22995417

VL - 167

SP - 2944

EP - 2951

JO - International Journal of Cardiology

JF - International Journal of Cardiology

SN - 0167-5273

IS - 6

ER -

ID: 36811735