Patients with medium-chain acyl-coenzyme a dehydrogenase deficiency have impaired oxidation of fat during exercise but no effect of L-carnitine supplementation

K L Madsen; N Preisler; M C Orngreen; S P Andersen; J H Olesen; A M Lund; J Vissing

doi:10.1210/jc.2012-3791

Patients with medium-chain acyl-coenzyme a dehydrogenase deficiency have impaired oxidation of fat during exercise but no effect of L-carnitine supplementation

K L Madsen, N Preisler, M C Orngreen, S P Andersen, J H Olesen, A M Lund, J Vissing

21 Citations (Scopus)

Abstract

It is not clear to what extent skeletal muscle is affected in patients with medium-chain acyl-coenzyme A dehydrogenase deficiency (MCADD). l-Carnitine is commonly used as a supplement in patients with MCADD, although its beneficial effect has not been verified.

Original language	English
Journal	The Journal of clinical endocrinology and metabolism
Volume	98
Issue number	4
Pages (from-to)	1667-75
Number of pages	9
ISSN	0021-972X
DOIs	https://doi.org/10.1210/jc.2012-3791
Publication status	Published - Apr 2013

Keywords

Acyl-CoA Dehydrogenase
Adolescent
Adult
Carnitine
Dietary Supplements
Exercise
Exercise Test
Exercise Tolerance
Female
Humans
Lipid Metabolism
Lipid Metabolism, Inborn Errors
Male
Oxidation-Reduction
Research Design
Young Adult

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Madsen, K. L., Preisler, N., Orngreen, M. C., Andersen, S. P., Olesen, J. H., Lund, A. M., & Vissing, J. (2013). Patients with medium-chain acyl-coenzyme a dehydrogenase deficiency have impaired oxidation of fat during exercise but no effect of L-carnitine supplementation. The Journal of clinical endocrinology and metabolism, 98(4), 1667-75. https://doi.org/10.1210/jc.2012-3791

Patients with medium-chain acyl-coenzyme a dehydrogenase deficiency have impaired oxidation of fat during exercise but no effect of L-carnitine supplementation. / Madsen, K L; Preisler, N ; Orngreen, M C et al.
In: The Journal of clinical endocrinology and metabolism, Vol. 98, No. 4, 04.2013, p. 1667-75.

Research output: Contribution to journal › Journal article › Research › peer-review

Madsen, KL, Preisler, N , Orngreen, MC, Andersen, SP, Olesen, JH, Lund, AM & Vissing, J 2013, 'Patients with medium-chain acyl-coenzyme a dehydrogenase deficiency have impaired oxidation of fat during exercise but no effect of L-carnitine supplementation', The Journal of clinical endocrinology and metabolism, vol. 98, no. 4, pp. 1667-75. https://doi.org/10.1210/jc.2012-3791

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keywords = "Acyl-CoA Dehydrogenase, Adolescent, Adult, Carnitine, Dietary Supplements, Exercise, Exercise Test, Exercise Tolerance, Female, Humans, Lipid Metabolism, Lipid Metabolism, Inborn Errors, Male, Oxidation-Reduction, Research Design, Young Adult",

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AU - Olesen, J H

AU - Lund, A M

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KW - Exercise Test

KW - Exercise Tolerance

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Patients with medium-chain acyl-coenzyme a dehydrogenase deficiency have impaired oxidation of fat during exercise but no effect of L-carnitine supplementation

Abstract

Keywords

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